Study to Assess How Well Intraoperative Ventilation Predicts Air Leaks After Major Lung Surgery Using Thoracoscopy
Led by GCS Ramsay Santé pour l'Enseignement et la Recherche · Updated on 2026-03-30
100
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Air leaks from the lung after major pulmonary surgeries such as lobectomy or anatomical segmentectomy are caused by small openings in the lung lining due to surgical damage. These air leaks are common and can lead to prolonged hospital stays and increased healthcare costs. Although the leaks themselves are painless, the treatments required, like chest drains, often cause significant discomfort and can complicate recovery. Advances in minimally invasive lung surgery have made traditional air leak detection methods less effective, creating the need for new ways to identify leaks during surgery.
This study evaluates the use of intraoperative ventilation measurements to detect and predict air leaks during lung surgery performed by conventional or robotic thoracoscopy. Each patient will receive standard care with routine intraoperative ventilation and postoperative chest drainage to manage air leaks. Researchers aim to find a correlation between the volume of air leakage measured during surgery and after surgery, potentially identifying patients who might avoid chest drains and thus reduce postoperative pain and hospital time.
Participants will be monitored from the time of surgery until four weeks after, with researchers assessing the air leak volumes during and after the procedure. This includes routine follow-up care involving chest drains and observation of any complications. The primary outcome is the correlation between intraoperative and postoperative air leak volumes, which will help guide future care to improve recovery and reduce discomfort following lung surgery.
CONDITIONS
Brief Title
Prospective Study Evaluating the Effectiveness of Intraoperative Ventilation for Predicting Postoperative Air Leaks During Major Lung Resections by Conventional or Robotic Thoracoscopy
Research Team
D
Dr Madalina GRIGOROIU
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match. Sign up to get personalized trial recommendations delivered to your inbox.
GCS Ramsay Santé pour l'Enseignement et la Recherche
Lead Sponsor
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
Patient with pulmonary lobectomy or anatomical segmentectomy using closed chest surgery (conventional or robotic thoracoscopy)
Patient affiliated with a health insurance scheme
Person who has not objected to the collection of their data for the purpose of the study
You will not qualify if you...
Patient undergoing any lung resection by thoracotomy
Patient with history of thoracic surgery on the same side
Patient with pulmonary fibrosis
Patient from a vulnerable population as defined in French Public Health Code articles L.1121-5 to 8
Patient undergoing conversion to thoracotomy
Patient undergoing conversion from planned lobectomy or segmentectomy to atypical resection, bilobectomy, or pneumonectomy
Use of two chest drains for drainage
Absence of autonomous drainage system
Patient not extubated at the end of the procedure
Early reoperation before drain removal due to complications
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Surgery and Immediate Post-operative Care
Duration - Surgery day and immediate post-operative period
Participants undergo major lung resection by conventional or robotic thoracoscopy. During surgery, intraoperative ventilation is used to diagnose air leaks. After surgery, participants receive routine post-operative care including installation of chest drains.
1 surgical visit and hospital stay for post-operative care
Post-operative Follow-up
Duration - Up to 4 weeks after surgery
Participants are monitored for post-operative air leaks and recovery following lung resection surgery.
Approximately 3 to 4 follow-up visits during the 4 weeks post-surgery
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Similar Trials
Study of New Methods to Detect and Treat Air Leaks During Lung Surgery Using an Ex-Vivo Human Lung Model
Auricular Acupressure to Support Prehabilitation Before Major Lung Surgery in Adults 50 and Older
Assessing a New Chest Drain Gas Analyzer Device to Detect Air Leaks After Lung Surgery
Study on Early Chest Tube Removal After Video Assisted Thoracic Surgery
Evaluating Safety and Patient Outcomes Following Lung Segment or Lobe Resection
Short-Term Atorvastatin Treatment to Prevent Atrial Fibrillation After Lung Surgery in Adults 60 and Older
Study to Assess How Well Intraoperative Ventilation Predicts Air Leaks After Major Lung Surgery Using Thoracoscopy
Right Ventricle Function After Major Lung Removal Surgery
Comparing Minimally Invasive Techniques VATS and Robotic Surgery and Open Surgery
Evaluating Safety and Survival of Neoadjuvant Immunotherapy in Surgery and Radiotherapy for Non-Small Cell Lung Cancer in a Real-World Study
Study to Test Aerosol Glycerine System for Finding Lung Air Leaks During Surgery
Have more questions? Get in touch with our team for quick support
Published Research Related To This Trial
NODRAIN study protocol: a non-interventional, prospective study for evaluating the effectiveness of intraoperative ventilation for the prediction of postoperative air leak in major pulmonary resections by conventional or robotic thoracoscopy.
Madalina Grigoroiu, Emmanuel Brian, Elisabeth Gauci...