Actively Recruiting
Protein Molecular Characteristics and Prognosis of Cervical Neuroendocrine Tumors
Led by Fujian Maternity and Child Health Hospital · Updated on 2024-09-19
300
Participants Needed
9
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying cervical neuroendocrine tumors by collecting clinical diagnosis and treatment data from 300 patients. This includes information like age, biopsy results, histopathology, and follow-up survival data. The goal is to analyze the molecular characteristics and prognosis of this cancer type to better understand its behavior and potential clinical applications. The study also gathers paraffin tissue samples from 100 cases across multiple centers to perform protein concentration and omics analyses. These tests help establish molecular features and identify prognostic markers of cervical neuroendocrine tumors. Participants' medical and follow-up data are reviewed to assess outcomes such as mortality rate and disease-free survival within three years after surgery. The study builds a database to support ongoing research and analysis of cervical neuroendocrine tumors' protein profiles and patient prognosis.
CONDITIONS
Brief Title
Protein Molecular Characteristics and Prognosis of Cervical Neuroendocrine Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with cervical neuroendocrine carcinoma by histopathology
- Complete clinical data available
You will not qualify if you...
- Not receiving treatment at the study hospital
- Lack of follow-up data or survival information
- Refusal to participate in the study
- Paraffin tissue samples do not meet quality requirements for protein analysis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Varies per participant depending on data availability
Participants undergo collection of clinical diagnosis and treatment data, including clinical and medical information such as age, preoperative HPV genotyping, biopsy and histopathological results, staging, prognosis, and survival information.
Data collection from medical records; no additional visits required
Duration - One-time tissue sample processing period
Protein and other molecular analyses are performed on paraffin tissue samples collected from participants to establish molecular characteristics and prognostic targets.
No additional visits; tissue samples are processed from existing paraffin blocks
Duration - Up to 3 years following surgery
Participants are followed for up to 3 years after surgery to monitor mortality rate and disease-free survival.
Follow-up visits and data collection as per routine clinical care
Trial Site Locations
Total: 9 locations
1
Fujian Maternity and Child Health Hospital
Fuzhou, Fujian, China, 350001
Actively Recruiting
2
Fujian Provincial Hospital
Fuzhou, Fujian, China
Actively Recruiting
3
Ningde Mindong Hospital
Ningde, Fujian, China
Actively Recruiting
4
Putian City first Hospital
Putian, Fujian, China
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5
The Second Affiliated Hospital of Fujian Medical University
Quanzhou, Fujian, China
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6
Zhangzhou affiliated Hospital of Fujian Medical University
Zhangzhou, Fujian, China, 363000
Actively Recruiting
7
Maternal and Child Health Hospital of Hubei Province
Wuhan, Hubei, China
Actively Recruiting
8
Xiangya Hospital, Central South University
Changsha, Hunan, China
Actively Recruiting
9
Jiangxi maternal and Child Health Hospital
Nanchang, Jiangxi, China
Actively Recruiting
Research Team
B
Binhua Dong
P
Pengming Sun
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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