Using Radiolabeled Nectin-4 Targeted Probe with PETCT to Detect Lung Lesions in Adults

What this Trial Is About

Researchers are evaluating the ability of 68GaN188, a radiolabelled probe targeting nectin-4, to detect overexpression of nectin-4 in patients with various lung lesions, including inflammation and lung cancer. This observational study aims to improve diagnostic imaging for these conditions by assessing the probes uptake in affected lung tissue. Participants will undergo PETCT imaging using the 68GaN188 probe to identify nectin-4 expression. Additionally, all participants will have an 18F-FDG PETCT scan within one week as part of the study procedures. The study includes adults between 18 and 75 years old and includes measures to ensure participant safety and compliance. During the study, participants will be assessed through imaging scans and clinical follow-up to measure the standardized uptake value SUV of the probe over one year. Researchers will monitor heart function and other health parameters to ensure safety. Participants are expected to comply with follow-up visits and may undergo pregnancy testing and contraception use if applicable. The total study period includes initial imaging and long-term observation of imaging outcomes.

Radiolabelled Nectin-4 Targeted LMW Probe PET/CT in Patients With Lung Lesions