Actively Recruiting
Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma
Led by AbbVie · Updated on 2026-02-17
700
Participants Needed
73
Research Sites
335 weeks
Total Duration
On this page
Sponsors
A
AbbVie
Lead Sponsor
G
Genmab
Collaborating Sponsor
AI-Summary
What this Trial Is About
Diffuse large B-cell lymphoma (DLBCL) is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections) and the most common type of non-Hodgkin lymphoma. Follicular Lymphoma (FL) is a slow-growing type of non-Hodgkin lymphoma. The purpose of this study is to assess the real-world effectiveness of subcutaneous epcoritamab in adult participants with advanced DLBCL and FL. Epcoritamab is an investigational drug being developed for treating participants with DLBCL and FL. Approximately 700 participants will be enrolled in approximately 80 sites across 12-20 countries globally. Participants will receive epcoritamab as prescribed by their physician in accordance with local country label. Participants will be followed for up to 3 years. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.
CONDITIONS
Official Title
Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled to be treated with epcoritamab after two or more prior therapies for 3L+ diffuse large B-cell lymphoma or 3L+ follicular lymphoma
- Treatment with epcoritamab administered according to the approved local label
- Treatment decision made by clinician before and independently of study participation
You will not qualify if you...
- Any condition listed as a contraindication in the approved local epcoritamab label
- Participation in another interventional clinical trial during enrollment and throughout this study (except non-interventional or observational studies, post-marketing observational studies, or registries)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 73 locations
1
Hospital Britanico de Buenos Aires /ID# 274419
Ciudad Autonoma de Buenos Aire, Buenos Aires, Argentina, 1280
Actively Recruiting
2
Hospital Universitario Austral /ID# 274393
Pilar, Buenos Aires, Argentina, 1629
Actively Recruiting
3
Instituto Alexander Fleming /ID# 277284
Ciudad Autonoma de Buenos Aire, Buenos Aires F.D., Argentina, 1426
Actively Recruiting
4
Hospital Privado Universitario De Córdoba /ID# 274457
Córdoba, Córdoba Province, Argentina, 5016
Actively Recruiting
5
Hospital Italiano de Buenos Aires /ID# 274418
Buenos Aires, Argentina, 1181
Actively Recruiting
6
Fundacion Argentina contra la Leucemia (FUNDALEU) /ID# 274390
Buenos Aires, Argentina, 1227
Actively Recruiting
7
Nepean Cancer Centre, Nepean Hospital /ID# 277782
Kingswood, New South Wales, Australia, 2747
Actively Recruiting
8
Calvary Mater Newcastle /ID# 277783
Waratah, New South Wales, Australia, 2298
Actively Recruiting
9
Cabrini Hospital Malvern /ID# 277780
Malvern, Victoria, Australia, 3144
Actively Recruiting
10
Krankenhaus Der Barmherzigen Brueder Graz /ID# 273288
Graz, Styria, Austria, 8020
Actively Recruiting
11
Landeskrankenhaus Hochsteiermark, Standort Leoben /ID# 273266
Leoben, Styria, Austria, 8700
Actively Recruiting
12
Algemeen Ziekenhuis klina /ID# 273405
Brasschaat, Antwerpen, Belgium, 2930
Actively Recruiting
13
Universitair Ziekenhuis Brussel /ID# 273403
Jette, Brussels Capital, Belgium, 1090
Actively Recruiting
14
Centre Hospitalier Epicura - Hornu /ID# 273406
Boussu, Hainaut, Belgium, 7301
Actively Recruiting
15
Grand Hôpital De Charleroi - Notre Dame /ID# 273728
Charleroi, Hainaut, Belgium, 6000
Actively Recruiting
16
Helora /ID# 273726
La Louvière, Hainaut, Belgium, 7100
Actively Recruiting
17
Groupe Sante CHC - Clinique du MontLegia /ID# 273407
Liège, Liege, Belgium, 4000
Actively Recruiting
18
Ziekenhuis Oost-Limburg, Campus St.-Jan /ID# 273729
Genk, Limburg, Belgium, 3600
Actively Recruiting
19
Vitaz /Id# 273408
Sint-Niklaas, Oost-Vlaanderen, Belgium, 9100
Actively Recruiting
20
AZ Oostende /ID# 273714
Ostend, West-Vlaanderen, Belgium, 8400
Actively Recruiting
21
Umhat Sveti Ivan Rilsky /ID# 274898
Sofiya, Sofia, Bulgaria, 1606
Actively Recruiting
22
University Multiprofile Hospital for Active Treatment Dr. Georgi Stranski /ID# 274893
Pleven, Bulgaria, 5800
Actively Recruiting
23
Acibadem City Clinic Tokuda University Hospital EAD /ID# 273659
Sofia, Bulgaria, 1407
Actively Recruiting
24
Specialized Hospital For Active Treatment Of Haematology Diseases /ID# 274955
Sofia, Bulgaria, 1756
Actively Recruiting
25
Cross Cancer Institute /ID# 271504
Edmonton, Alberta, Canada, T6G 1Z2
Actively Recruiting
26
The Moncton Hospital /ID# 277230
Moncton, New Brunswick, Canada, E1C 6Z8
Actively Recruiting
27
Eastern Health - General Hospital /ID# 272062
St. John's, Newfoundland and Labrador, Canada, A1B 3V6
Actively Recruiting
28
Health Sciences North /ID# 274738
Greater Sudbury, Ontario, Canada, P3E 5J1
Actively Recruiting
29
Kingston General Hospital /ID# 272061
Kingston, Ontario, Canada, K7L 2V7
Actively Recruiting
30
Agios Andreas Hospital Patras /ID# 273629
Pátrai, Achaia, Greece, 26335
Actively Recruiting
31
Evangelismos Hospital /ID# 272736
Athens, Attica, Greece, 10676
Actively Recruiting
32
General Hospital of Athens Laiko /ID# 272758
Athens, Attica, Greece, 11527
Actively Recruiting
33
University General Hospital Attikon /ID# 272738
Athens, Attica, Greece, 12462
Actively Recruiting
34
Metaxa Cancer Hospital Of Piraeus /ID# 273623
Piraeus, Attica, Greece, 18537
Actively Recruiting
35
University General Hospital of Alexandroupoli /ID# 272737
Alexandroupoli, Evros, Greece, 68100
Actively Recruiting
36
University Hospital of Ioannina /ID# 272739
Ioannina, Greece, 45500
Actively Recruiting
37
AHEPA University General Hospital of Thessaloniki /ID# 273633
Thessaloniki, Greece, 54636
Actively Recruiting
38
General Hospital of Thessaloniki Hippokrateio /ID# 273635
Thessaloniki, Greece, 54642
Actively Recruiting
39
Papageorgiou General Hospital /ID# 272735
Thessaloniki, Greece, 56429
Actively Recruiting
40
General Hospital Of Thessaloniki G. Papanikolaou /ID# 275323
Thessaloniki, Greece, 57010
Actively Recruiting
41
Tel Aviv Sourasky Medical Center /ID# 271615
Tel Aviv, Tel Aviv, Israel, 6423906
Actively Recruiting
42
Hadassah Medical Center-Hebrew University /ID# 271616
Jerusalem, Israel, 91120
Actively Recruiting
43
Rabin Medical Center. /ID# 271614
Petah Tikva, Israel, 4941492
Actively Recruiting
44
IRCCS Ospedale San Raffaele /ID# 274789
Milan, Milano, Italy, 20132
Actively Recruiting
45
Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli /ID# 274215
Naples, Napoli, Italy, 80131
Actively Recruiting
46
A.O.U. CITTA' DELLA SALUTE E DELLA SCIENZA DI TORINO - Ospedale Molinette /ID# 275283
Turin, Piedmont, Italy, 10126
Actively Recruiting
47
Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 274572
Rome, Roma, Italy, 00133
Actively Recruiting
48
I.R.C.C.S Istituto Tumori Giovanni Paolo II /ID# 274217
Bari, Italy, 70124
Actively Recruiting
49
Ospedale La Maddalena /ID# 274411
Palermo, Italy, 90146
Actively Recruiting
50
Hematologica Alta Especialidad /ID# 275279
Huixquilucan de Degollado, Mexico, 52787
Actively Recruiting
51
Centro de Especialidades Hemato-Oncologicas /ID# 275286
Mexico City, Mexico, 11520
Actively Recruiting
52
Unidade Local de Saude de Coimbra, EPE /ID# 272720
Coimbra, Portugal, 3000-075
Actively Recruiting
53
Unidade Local de Saúde Trás-os-Montes e Alto Douro /ID# 275404
Vila Real, Portugal, 5000-185
Actively Recruiting
54
Complejo Hospitalario Universitario A Coruña /ID# 272040
A Coruña, A Coruna, Spain, 15006
Actively Recruiting
55
Institut Català d'Oncologia (ICO) - Badalona /ID# 272043
Badalona, Barcelona, Spain, 08916
Actively Recruiting
56
Hospital Universitari Parc Tauli /ID# 272044
Sabadell, Barcelona, Spain, 08208
Actively Recruiting
57
Hospital Universitario Reina Sofia /ID# 272051
Córdoba, Cordoba, Spain, 14004
Actively Recruiting
58
Hospital Costa del Sol /ID# 272431
Marbella, Malaga, Spain, 29603
Actively Recruiting
59
Hospital Universitario de Navarra /ID# 272041
Pamplona, Navarre, Spain, 31008
Actively Recruiting
60
Hospital Universitario de Valme /ID# 272050
Seville, Sevilla, Spain, 41014
Actively Recruiting
61
Hospital de Manises /ID# 272046
Manises, Valencia, Spain, 46940
Actively Recruiting
62
Hospital Universitario De Burgos /ID# 272066
Burgos, Spain, 09006
Actively Recruiting
63
Hospital General Universitario Morales Meseguer /ID# 272466
Murcia, Spain, 30008
Actively Recruiting
64
Hospital Universitario Nuestra Señora de Candelaria /ID# 272413
Santa Cruz de Tenerife, Spain, 38010
Actively Recruiting
65
Hospital Clinico Universitario de Valladolid /ID# 272042
Valladolid, Spain, 47003
Actively Recruiting
66
Milton Keynes Hospital /ID# 272817
Milton Keynes, Buckinghamshire, United Kingdom, MK6 5LD
Actively Recruiting
67
Royal Cornwall Hospital /ID# 272747
Truro, Cornwall, United Kingdom, TR1 3LQ
Actively Recruiting
68
Cheltenham General Hospital /ID# 272746
Cheltenham, Gloucestershire, United Kingdom, GL53 7AN
Actively Recruiting
69
Queen Alexandra Hospital /ID# 272744
Portsmouth, Hampshire, United Kingdom, PO6 3LY
Actively Recruiting
70
NHS Lanarkshire /ID# 276471
Airdrie, North Lanarkshire, United Kingdom, ML6 0JS
Actively Recruiting
71
Nottingham City Hospital /ID# 272753
Nottingham, Nottinghamshire, United Kingdom, NG5 1PB
Actively Recruiting
72
The Christie /ID# 272745
Manchester, United Kingdom, M20 4BX
Actively Recruiting
73
The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 272748
Newcastle upon Tyne, United Kingdom, NE3 3HD
Actively Recruiting
Research Team
R
Rebekah Taylor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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