Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT05862259

A Real-world Study of the Efficacy and Safety of ICIs as First-line Therapy for Advanced Malignancies

Led by Xinqiao Hospital of Chongqing · Updated on 2025-07-14

120

Participants Needed

1

Research Sites

124 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this study, we collected the data of immunohistochemistry, gene detection, image, OS, PFS, Orr, and so on. Secondly, the database of immunotherapy for malignant tumor was established, and the predictive model was constructed to verify and establish the rationality and validity of the biomarkers and predictive system of immunotherapy

CONDITIONS

Official Title

A Real-world Study of the Efficacy and Safety of ICIs as First-line Therapy for Advanced Malignancies

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent and ability to follow the study protocol
  • Diagnosed with advanced malignant solid tumors such as non-small-cell lung carcinoma, stomach, breast, or urinary system cancer confirmed by histopathology
  • Cancer stage IV according to the eighth edition of IASLC
  • Performance status (PS) between 0 and 2 with expected survival over 3 months
  • Age between 18 and 75 years
  • No contraindications to treatment with immune checkpoint inhibitors
Not Eligible

You will not qualify if you...

  • Poor compliance violating study rules
  • Severe dysfunction of vital organs including heart, liver, or kidneys
  • Presence of other malignant tumors
  • Investigator's judgment that participation is not suitable for the patient

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

the second affiliated hospital of Army medical university

Chongqing, Chongqing Municipality, China, 40037

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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