Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT04095195

Registry of Subjects at Risk of Pancreatic Cancer

Led by Associazione Italiana per lo Studio del Pancreas · Updated on 2023-01-13

1000

Participants Needed

4

Research Sites

1361 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

IRFARPC is a multicenter national registry designed to study the diagnosis and predisposing factors of subjects with an inherited increased risk for pancreatic cancer.

CONDITIONS

Official Title

Registry of Subjects at Risk of Pancreatic Cancer

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals with at least two relatives with pancreatic cancer, including at least one first-degree relative and up to third-degree relatives
  • Subjects with known BRCA2, BRCA1, p16, or PALB2 genetic mutations and at least one first- or second-degree relative with pancreatic cancer
  • Subjects diagnosed with FAMMM Syndrome
  • Subjects diagnosed with Peutz-Jeghers Syndrome
  • Subjects with PRSS-1-, CFTR-, or SPINK-1-related pancreatitis
  • Subjects diagnosed with Lynch syndrome and at least one first- or second-degree relative with pancreatic cancer
  • For radiologic follow-up: age 45 years or 10 years younger than youngest family pancreatic cancer case for familial cases
  • For radiologic follow-up: age 40 years or 5 years younger than youngest pancreatic cancer case for hereditary/genetic pancreatitis, Lynch syndrome, or BRCA1/2, PALB2, p16 mutation carriers with family history
  • For radiologic follow-up: age 30 years for subjects with FAMMM or Peutz-Jeghers syndrome
Not Eligible

You will not qualify if you...

  • Pregnancy

AI-Screening

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Trial Site Locations

Total: 4 locations

1

Istituto Clinico Humanitas

Rozzano, Milan, Italy

Actively Recruiting

2

Ospedale Pederzoli

Peschiera del Garda, Verona, Italy

Actively Recruiting

3

San Raffele Vita Salute University Hospital

Milan, Italy

Actively Recruiting

4

Chirurgia Generale e del Pancreas

Verona, Italy, 37134

Actively Recruiting

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Research Team

S

Salvatore Paiella, MD, PhD

CONTACT

S

Silvia Carrara, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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