Actively Recruiting

Age: 19Years +
All Genders
NCT06243653

Relationship Between Coronary Microvascular Dysfunction and Improvement of Left Ventricular Systolic Function in Patients With Heart Failure With Reduced Ejection Fraction Caused by Non-ischemic Etiology

Led by Samsung Medical Center · Updated on 2024-02-06

200

Participants Needed

1

Research Sites

229 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the incidence of coronary microvascular dysfunction (CMD) and its prognostic implication for the improvement of left ventricular function in patients who have been diagnosed with heart failure with reduced ejection fraction (HFrEF) caused by non-ischemic etiology.

CONDITIONS

Official Title

Relationship Between Coronary Microvascular Dysfunction and Improvement of Left Ventricular Systolic Function in Patients With Heart Failure With Reduced Ejection Fraction Caused by Non-ischemic Etiology

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 19 years old
  • Symptoms or signs of heart failure with New York Heart Association class 2 or higher dyspnea
  • Left ventricular ejection fraction 40% or less
  • Clinical need for coronary angiography
  • Able to voluntarily sign informed consent form
Not Eligible

You will not qualify if you...

  • Significant coronary artery stenosis on angiography (90% or more diameter narrowing, or 50-90% with fractional flow reserve 0.80 or less)
  • Scheduled for heart transplant or left ventricular assist device implantation
  • Heart failure due to restrictive cardiomyopathy, active myocarditis, or constrictive pericarditis
  • Significant valvular heart disease requiring surgery
  • Non-cardiac illnesses with life expectancy less than 1 year

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Samsung Medical Center

Seoul, South Korea

Actively Recruiting

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Research Team

K

Ki Hong Choi, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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