Actively Recruiting

Age: 18Years - 80Years
All Genders
Healthy Volunteers
ID06742580

The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients

Led by Murat Akın · Updated on 2024-12-19

80

Participants Needed

3

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Bell's palsy, also called acute facial palsy of unknown cause, is a common nerve condition that causes sudden weakness or paralysis on one side of the face. It often comes with symptoms like pain behind the ear, taste changes, altered facial sensation, and sensitivity to sound. This research aims to explore the relationship between blood homocysteine levels—a substance linked to blood clotting disorders—and idiopathic acute peripheral facial paralysis, as no previous studies have investigated this connection. The study observes two groups: patients who have recently developed idiopathic facial paralysis and healthy individuals without known health issues. Blood homocysteine levels will be measured and compared between these groups. This observational study will follow participants to measure homocysteine over a period of up to 24 weeks. During the study, participants will be monitored through blood tests to assess homocysteine levels. Researchers will evaluate these results to understand if higher homocysteine is related to facial paralysis. The study includes adults aged 18 to 80 years and involves healthy volunteers as a control group. The total participation duration covers up to 24 weeks, with ongoing monitoring of blood test results.

CONDITIONS

Brief Title

The Relationship Between Idiopathic Acute Peripheral Facial Paralysis and Homocysteine Level in Adult Patients

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients admitted with acute facial paralysis
Not Eligible

You will not qualify if you...

  • Facial and ear trauma or tumor
  • İatrogenic
  • Cholesteatoma
  • Facial paralysis due to central nervous system diseases

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Up to 24 weeks

Participants undergo blood tests to measure homocysteine levels and assessments related to idiopathic acute peripheral facial paralysis.

1 to 2 visits depending on group assignment

Trial Site Locations

Total: 3 locations

1

Afyonkarahisar Health Sciences University

Afyonkarahisar, Turkey (Türkiye)

Active, Not Recruiting

2

Afyonkarahisar Health Sciences University

Afyonkarahisar, Turkey (Türkiye)

Actively Recruiting

3

Afyonkarahisar Health Sciences University

Afyonkarahisar, Turkey (Türkiye)

Actively Recruiting

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Research Team

M

MURAT AKIN, ASSISTANT DOCTOR

O

Orhan Kemal KAHVECİ, PROFESSOR

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial