Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05650905

Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19

Led by Medical University of Vienna · Updated on 2025-05-16

90

Participants Needed

1

Research Sites

231 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The Study objective is to measure retinal neurovascular coupling and blood flow parameters in patients previously infected with COVID-19, long COVID-19 and healthy age- and sex- matched control subjects

CONDITIONS

Official Title

Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged over 18 years
  • Non-smokers
  • For healthy subjects: no history of COVID-19 infection, negative SARS-CoV-2 nucleocapsid antibody and PCR tests, and normal eye exam with ametropy less than 6 diopters
  • For subjects with history of COVID-19: positive PCR test within last 6 months, positive spike protein IgG antibody test, negative PCR test at study
  • For subjects with long COVID-19: history of COVID-19 with positive seroprevalence, negative PCR test, and meeting WHO criteria for long COVID-19
Not Eligible

You will not qualify if you...

  • Symptoms of significant illness within 3 weeks before study day
  • Severe medical conditions as judged by investigator
  • Participation in another clinical trial within 3 weeks before study
  • Blood donation within previous 3 weeks
  • History or family history of epilepsy
  • Abnormalities preventing reliable eye measurements
  • Best corrected visual acuity less than 0.8 Snellen
  • Pregnancy, planned pregnancy, or lactation
  • Ametropy greater than 6 diopters (for COVID-19 and long COVID-19 groups)
  • History of epilepsy
  • Diabetes mellitus (for long COVID-19 group)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Medical University of Vienna, Department of Clinical Pharmacology

Vienna, State of Vienna, Austria, 1090

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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