Actively Recruiting
A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae
Led by Mayo Clinic · Updated on 2026-05-07
67
Participants Needed
1
Research Sites
185 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to understand why some people experience long term effects, such as shortness of breath and fatigue, after a severe COVID-19 infection
CONDITIONS
Official Title
A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older at screening
- For Sequelae Group: PCR confirmed COVID-19 illness with hospitalization, no pre-existing interstitial lung disease or significant lung disease
- Severity categorized as moderate (oxygen 1-8L), severe (high flow oxygen 8L or more), or critical illness (ICU or mechanical ventilation)
- For Control Recovery Group: Age 18 years or older, PCR confirmed COVID-19 with mild or no symptoms, no hospitalization, no ongoing respiratory or systemic symptoms, no pre-existing interstitial lung disease or significant lung disease
You will not qualify if you...
- Unable to provide informed consent
- Pre-existing interstitial lung disease or chronic lung disease
- Active cigarette smoking, vaping, or other inhalation use
- Immunocompromised due to ongoing therapy with methotrexate, CellCept, azathioprine, rituximab, cyclophosphamide, or other biologic agents
- More than 20 pack-year smoking history
- History of chemotherapy or radiation therapy in the last two years
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic Minnesota
Rochester, Minnesota, United States, 55905
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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