Actively Recruiting

All Genders
ID04569162

Rhizomelic Chondrodysplasia Punctata Registry at Nemours Children's Health

Led by Nemours Children's Clinic · Updated on 2025-07-11

100

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

N

Nemours Children's Clinic

Lead Sponsor

R

RhizoKids International

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to collect detailed medical information on individuals diagnosed with rhizomelic chondrodysplasia punctata (RCDP) and closely related conditions. The purpose is to better understand the natural history of these rare disorders and identify clinical features that may predict poor outcomes. By establishing this registry, the study hopes to support future development of preventive treatments and improve quality of life for those affected. The study involves only reviewing existing medical records, including specialist evaluations, surgical reports, blood and urine tests, genetic testing, and imaging like x-rays or CT/MRI scans. There are no additional visits, procedures, or tests required for participants. No treatments or interventions are administered as part of this registry. Participants will not need to attend any study visits or change their usual care. Researchers will securely collect and store data extracted from medical charts to analyze disease progression and outcomes over a five-year period. The study is observational and poses no direct risk, focusing solely on data collection and analysis with ongoing monitoring until 2030.

CONDITIONS

Brief Title

Rhizomelic Chondrodysplasia Punctata Registry

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with RCDP or closely related conditions by metabolic and/or genetic testing
Not Eligible

You will not qualify if you...

  • Not meeting diagnosis of RCDP or closely related conditions by study team physician review of prior metabolic and/or genetic testing

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote) for consent and eligibility confirmation

Long-term Monitoring

Duration - Up to 5 years

Participants who undergo routine care are observed through collection of existing medical records and data to study the natural history of RCDP without additional clinic visits or procedures.

No additional visits; data collected from routine healthcare records

Trial Site Locations

Total: 1 location

1

Nemours

Wilmington, Delaware, United States, 19803

Actively Recruiting

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Research Team

E

Emily Longenecker, BS

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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