Actively Recruiting

Phase Not Applicable
Age: 19Years - 99Years
All Genders
Healthy Volunteers
ID06827444

Effects of Attention and Placebo Modulation on Cycling Performance: an Experimental Study on Stationary Bikes

Led by Catholic University of the Sacred Heart · Updated on 2025-02-14

128

Participants Needed

1

Research Sites

20 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how different types of attention to sensory information can influence the connection between the mind and body, focusing on the placebo effect. The study explores mindful attention to improve how likely outcomes are perceived and directed attention to change outcome expectations, aiming to understand how these forms of attention can modify the placebo effect during physical activity. The study involves 128 healthy adults cycling on stationary bikes for about 60 minutes with alternating phases of attention manipulation. After a warm-up, participants receive a placebo drink described as "highly stimulating." A separate control group of 32 participants completes the cycling without the placebo or attention manipulation. Heart rate monitors and cycling performance data will be collected during exercise without feedback to participants. Participants will undergo pre-intervention assessments, and their heart rate, emotions, and perceived fatigue will be tracked throughout the cycling session and recovery. The main outcome measured is fatigue at 30 minutes, with secondary outcomes including heart rate and perceived effectiveness of the placebo drink. The study is randomized with single blinding and is conducted by the Catholic University of the Sacred Heart.

CONDITIONS

Brief Title

The Role of Attention in Modulating the Placebo Effect

Who Can Participate

Age: 19Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Persons aged 18 years or older in good health, confirmed by a medical certificate
  • Willing and able to attend gym sessions; admission cost covered by the project if not enrolled
Not Eligible

You will not qualify if you...

  • Known cardiovascular diseases
  • Gastrointestinal diseases
  • Musculoskeletal injuries
  • Upper respiratory tract infections
  • Allergy or intolerance to caffeine

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Approximately 30 minutes per session

Participants perform cycling sessions wearing a heart rate chest strap. They complete a baseline warm-up followed by exercise tests without visual or verbal feedback. Heart rate and cycling performance data are recorded continuously during exercise and recovery. Participants are randomized to receive a placebo manipulation or control condition during the cycling tests.

1 session (in-person)

Trial Site Locations

Total: 1 location

1

Università Cattolica del Sacro Cuore

Milan, Milano, Italy, 20123

Actively Recruiting

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Research Team

F

Francesca NA Grosso, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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