Actively Recruiting

Phase Not Applicable
Age: 19Years - 99Years
All Genders
Healthy Volunteers
NCT06827444

The Role of Attention in Modulating the Placebo Effect

Led by Catholic University of the Sacred Heart · Updated on 2025-02-14

128

Participants Needed

1

Research Sites

60 weeks

Total Duration

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AI-Summary

What this Trial Is About

This project aims to examine whether these forms of attention to sensory information can modulate the mind-body interaction. This will be demonstrated through a study focused on the placebo effect with attention manipulation. Specifically, the project will focus on the construct of mindful attention to increase the precision of the likelihood and reduce the effects of priors, and on directed attention to modify the position and precision of the likelihood, hypothetically modulating the placebo effect. The study involves recruiting 128 healthy individuals, who will be asked to cycle on an ergometer for approximately 60 minutes, with alternating phases in which attention will be manipulated. After an initial warm-up phase, they will receive a placebo drink, presented as "highly stimulating." An additional group of 32 participants will not receive either the placebo drink or the attentional stimuli, but will undergo the same training cycles. All participants will receive a pre-intervention assessment, and heart rate, emotions, and perceived fatigue will be monitored.

CONDITIONS

Official Title

The Role of Attention in Modulating the Placebo Effect

Who Can Participate

Age: 19Years - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Persons aged 18 years or older in good health, confirmed by a medical certificate (sporting, competitive or non-competitive, or of good health)
  • Available to attend sessions at a gym; if not enrolled, admission costs are covered by the project
Not Eligible

You will not qualify if you...

  • Known cardiovascular diseases, gastrointestinal diseases, musculoskeletal injuries, or upper respiratory tract infections
  • Allergy or intolerance to caffeine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Università Cattolica del Sacro Cuore

Milan, Milano, Italy, 20123

Actively Recruiting

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Research Team

F

Francesca NA Grosso, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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The Role of Attention in Modulating the Placebo Effect | DecenTrialz