Actively Recruiting

Age: 18Years - 50Years
FEMALE
NCT07346833

Role of Circulating MicroRNAs in Differentiating Psychological Disorders Among Women With Chronic Toxoplasmosis

Led by Benha University · Updated on 2026-01-16

55

Participants Needed

1

Research Sites

18 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Chronic Toxoplasma gondii (T. gondii) infection is a widespread condition that can negatively affect brain function and is considered a risk factor for various psychiatric conditions, including depression and schizophrenia. This prospective observational study aims to investigate the expression levels of specific circulating microRNAs (miRNAs) in women diagnosed with schizophrenia, major depressive disorder, or bipolar disorder who also have chronic toxoplasmosis. By comparing these levels to patients without the infection, the study seeks to determine if these miRNAs can serve as biological markers to help differentiate between specific psychological disorders and identify the impact of chronic toxoplasmosis on mental health.

CONDITIONS

Official Title

Role of Circulating MicroRNAs in Differentiating Psychological Disorders Among Women With Chronic Toxoplasmosis

Who Can Participate

Age: 18Years - 50Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Women diagnosed with schizophrenia, major depressive disorder, or bipolar disorder according to DSM-5 criteria
  • Negative for T. gondii IgM to confirm no acute infection
  • Provided signed informed consent
Not Eligible

You will not qualify if you...

  • Diagnosed with psychiatric disorders other than schizophrenia, major depressive disorder, or bipolar disorder
  • Positive for T. gondii IgM indicating acute infection
  • Refusal to participate

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Benha faculty of Medicine

Banhā, El Qalyoubia, Egypt, 13511

Actively Recruiting

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Research Team

H

Heba Abo El Ela, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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