Actively Recruiting

Age: 18Years +
All Genders
NCT07085247

The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease

Led by Masaryk University · Updated on 2025-08-27

400

Participants Needed

1

Research Sites

187 weeks

Total Duration

On this page

Sponsors

M

Masaryk University

Lead Sponsor

S

St. Anne's University Hospital Brno, Czech Republic

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this study is to clarify the role of the bacterium Cutibacterium acnes in the development of degenerative disc disease in patients with lumbar disc herniation who underwent microdiscectomy as part of their regular medical care.

CONDITIONS

Official Title

The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • minimum age of 18 years
  • MRI of the lumbosacral spine performed one month ± 2weeks before surgery showing a disc protrusion, herniation, or free nucleus pulposus sequestration
  • matching physical examination findings including positive straight leg raise test, dermatomal sensory deficits, myotome motor deficits, and diminished deep tendon reflexes.
Not Eligible

You will not qualify if you...

  • antibiotics or corticosteroid use the month before surgery
  • ongoing bacterial or viral infection
  • immunocompromised patient
  • trauma
  • undefined radiological mass
  • inflammatory arthritis
  • other rheumatologic diseases.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

St. Anne´s University Hospital Brno

Brno, Czechia, 60200

Actively Recruiting

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Research Team

P

Peter Solár, MUDr., Ph.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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