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Evaluating Effects of Lever Positioning Manipulation on Lumbar Disc Herniation Using Different Triggering Methods and Biomechanical Analysis
Led by The Third Affiliated hospital of Zhejiang Chinese Medical University · Updated on 2025-03-12
128
Participants Needed
1
Research Sites
26 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the clinical effects and biomechanical impacts of different trigger modes of lever positioning manipulation LPM for treating lumbar disc herniation LDH. This study aims to clarify the clinical efficacy of LPM, analyze the mechanical and spatial motion characteristics of its two trigger modes, and explore how these modes influence the stress-strain and flow-solid coupling effects on the lumbar intervertebral discs, particularly at the L45 segment. The investigation also uses 3D finite element technology combined with dynamic capture and mechanical sensing systems to better understand these effects. Participants include 64 LDH patients and 64 healthy volunteers divided into four groups two patient groups receiving either unilateral or bilateral LPM or sham manipulation, and two healthy volunteer groups receiving unilateral or bilateral LPM. Treatments are administered every two days for a total of six sessions over two weeks. During manipulation, mechanical and kinematic data are collected using sensing gloves and motion capture systems. Additionally, a virtual simulation model is built from imaging data to analyze biomechanical loading and stress on the intervertebral discs under different LPM modes. Participants will complete clinical questionnaires such as the Visual Analog Scale VAS and Japanese Orthopaedic Association JOA scoring system to assess pain and function. Mechanical parameters and motion characteristics are recorded during manipulation sessions. Researchers will use these data alongside imaging and individual patient features to study correlations. The primary outcome is the overall clinical efficacy after two weeks. Secondary outcomes include pain and functional scores, as well as detailed mechanical and kinematic measurements during treatment.
CONDITIONS
Brief Title
A Biomechanical Study of the Lumbar Intervertebral Disc by Lever Positioning Manipulation
Research Team
L
Longhao Chen, Principal Investigator
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