Actively Recruiting
ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer
Led by West China Hospital · Updated on 2026-04-15
40
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Radiation dermatitis is a common complication in head and neck squamous cell carcinoma patients receiving radiotherapy. This study proposes an ROS-scavenging amino acid-based nanolipid to prevent oxidative skin damage. A multicenter randomized trial will evaluate its safety and efficacy in reducing dermatitis severity and improving treatment continuity.
CONDITIONS
Official Title
ROS-scavenging Amino Acid-derived Lipids for the Prevention and Treatment of Radiation Dermatitis in Patients With Head and Neck Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a pathological diagnosis of non-metastatic head and neck malignant tumors
- Patients suitable for high-dose radiotherapy as primary or postoperative treatment following surgery
You will not qualify if you...
- Eastern Cooperative Oncology Group performance status greater than 2
- Pre-existing skin rash, ulceration, or open wound in the treatment area
- Known allergy to trolamine or amino acid
- Inflammatory or connective tissue disorder of the skin
- History of head and neck radiotherapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
West China Hospital, Sichuan University
Chengdu, Sichuan, China
Actively Recruiting
Research Team
X
Xingchen Peng
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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