Actively Recruiting
SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom
Led by NHS Greater Glasgow and Clyde · Updated on 2024-07-16
400
Participants Needed
1
Research Sites
132 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aims of this prospective natural history study are to define the seizure, neuro-developmental, and behavioural characteristics of SCN1A-related epilepsies/Dravet syndrome in children and adults longitudinally over a period of three years. In addition, this study will compare missense and truncating genotypes in terms of i) rates of change of countable convulsive seizures per month and ii) neurodevelopmental outcome and trajectories.
CONDITIONS
Official Title
SCN1A Horizons A Natural History Study of SCN1A-related Epilepsies in the United Kingdom
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient or legally authorized representative must be willing and able to give informed consent or assent for study participation
- Patient and parent/caregiver must be willing and able to comply with all study requirements, including virtual visits
- Participant must have a confirmed pathogenic (class 5) or likely pathogenic (class 4) SCN1A variant shown by genetic testing
You will not qualify if you...
- Patient has any other significant disease or disorder that may put them at risk or affect their ability to participate in the study, as judged by the Investigator
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Royal Hospital for Children
Glasgow, United Kingdom, G51 4TF
Actively Recruiting
Research Team
K
Kirsty Hendry, PhD
CONTACT
A
Andreas Brunklaus, MD PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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