Actively Recruiting
Screening for Familial Hypercholesterolemia in Children
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2026-02-12
300
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Familial hypercholesterolemia is a common genetic disorder that causes very high LDL cholesterol levels, increasing the risk of early cardiovascular events. It affects both adults and children, with only a small proportion currently diagnosed and treated. Early screening, especially in children, is recommended to detect the condition before symptoms appear and to reduce long-term health risks. This trial is led by Centre Hospitalier Universitaire, Amiens, focusing on screening children for this condition. The study involves taking a 5-ml blood sample from children aged 2 to 18 years after a minimum 8-hour fasting to analyze lipid levels. This biological intervention aims to identify the prevalence of familial hypercholesterolemia in the general pediatric population. The research follows no masking or blinding and does not include a control or placebo group. Participants will provide informed consent, and the primary outcome measured is the prevalence of hypercholesterolemia in children at 16 months after screening. Blood samples will be sent to a lab for lipid analysis. The study includes safety monitoring and excludes children with known familial hypercholesterolemia or certain other health conditions. Participation involves a fasting blood draw and follow-up to assess cholesterol levels.
CONDITIONS
Brief Title
Screening for Familial Hypercholesterolemia in Children
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 2 and 18 years
- Minimum 8-hour fasting before blood sample
- Parents and children have signed informed consent
You will not qualify if you...
- Known familial hypercholesterolemia
- Diabetes diagnosed less than one month ago
- Profound hypothyroidism
- Acute nephrotic syndrome
- Cancer under treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Trial Site Locations
Total: 1 location
1
CHRU Amiens
Amiens, France, 80480
Actively Recruiting
Research Team
G
gwendoline Buissart, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
0
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