Actively Recruiting

Age: 18Years - 99Years
All Genders
NCT06615973

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

Led by National Institute of Neurological Disorders and Stroke (NINDS) · Updated on 2026-05-14

450

Participants Needed

1

Research Sites

36 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Background: Stroke is the fifth leading cause of death in the United States. It is also a leading cause of disability. More than 70% of people who survive strokes have mental impairment or dementia. Medical factors, such as the severity of the stroke, affect whether a person will have mental impairment afterward. But social factors, such as education and ethnicity, seem to play a role as well. Researchers want to learn more about how social and lifestyle factors affect a person s chances of maintaining mental functions after a stroke. Objective: To better understand how social and lifestyle factors affect the risk of mental impairment after a stroke. Eligibility: People aged 18 years and older who had a stroke and a brain scan while they were enrolled in NIH Study 01N0007 (Natural History of Stroke Study). Design: Participants will have 1 study visit, by telephone. The call will last about 45 minutes. Participants will talk about their health since their stroke. They will answer questions about themselves. Topics will include: * Their race * Education * Ethnicity * Employment * Marital status * Residence address * Recent health history * Medical insurance They will have tests of their memory, attention, and language skills. They will repeat numbers and words forward and backward. Researchers will look at the data and imaging scans collected during participant s enrollment in NIH Study 01N0007. This data will include: * The hospital that first saw the participant at the time of their stroke. * The type of imaging that was first used then. * The primary diagnosis at admission. * Other medical details.

CONDITIONS

Official Title

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willingness to comply with all study procedures and available for the study duration
  • Adults aged 18 years or older
  • Previous participant in the Natural History of Stroke study with an interpretable baseline MRI scan
  • NIH Stroke Scale measured at baseline or discharge
  • Admission diagnosis of ischemic stroke
  • Fluent in English or Spanish
Not Eligible

You will not qualify if you...

  • Modified Rankin Scale score of 6 at any follow-up (indicating death) in the Natural History of Stroke study

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

National Institutes of Health Clinical Center

Bethesda, Maryland, United States, 20892

Actively Recruiting

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Research Team

R

Rebecca F Gottesman, M.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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