Estimates of the prevalence of acute stroke impairments and disability in a multiethnic population.
E S Lawrence, C Coshall, R Dundas...
https://pubmed.ncbi.nlm.nih.gov/11387487/Actively Recruiting
Led by Ohio State University · Updated on 2026-07-23
12
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating a partially self-supervised constraint-induced movement therapy sCIMT program for adults who have arm and hand weakness after a stroke. This study aims to find out if the sCIMT program helps improve the use of the affected arm and hand, whether participants find the program useful and easy to follow, and if it improves quality of life and daily well-being. The trial is focused on treatment for adult stroke survivors with moderate upper extremity hemiparesis. Participants will undergo up to 30 hours of rehabilitation over 2 weeks, consisting of 3-hour sessions held up to 5 times per week. Each session combines one-third therapist-guided training with two-thirds self-supervised task practice. During therapy, participants will wear a mitt on the stronger hand to encourage use of the weaker arm. The exercises focus on task-oriented functional and non-functional activities designed to promote motor recovery and use of the affected arm. Throughout the study, participants will complete surveys and tests before and after the therapy program to measure changes in arm and hand use, experiences with the program, and quality of life. Assessments include the Action Research Arm Test, Fugl-Meyer Assessment, 9-Hole Peg Test, Motor Activity Log, Box and Block Test, grip and pinch strength, sensory testing, and interviews. Researchers will also monitor recruitment, retention, adherence, clinician time, protocol deviations, and adverse events. The total study duration around the intervention is approximately 2 to 4 weeks.
CONDITIONS
Self-Supervised Constraint-Induced Movement Therapy for Stroke Recovery
P
Peyton Miller
L
Lauren Wengerd
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Ohio State University
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Self-supervised Constraint-induced Movement Therapy (sCIMT) | Standard Occupational Therapy (Guideline-based Usual Care) |
|---|---|---|
| What it is | A structured upper limb rehabilitation program combining therapist-guided and self-directed practice, designed to promote use and recovery of the affected arm following stroke. | A therapist-supervised, task-oriented occupational therapy approach focused on upper extremity motor recovery, adapted to individual patient needs and mobility limitations. |
| Role in trial | The investigational intervention studied in all enrolled participants. | Included as contextual comparator for interpreting study results and understanding guideline-based routine care. |
| Primary use | To improve arm and hand function, promote greater use of the affected limb, and support overall motor recovery after stroke. | To restore functional upper extremity movement and skills, alleviate disability, and maximize independence following a stroke. |
| How it is given/performed | Participants receive up to 30 hours of sCIMT over 2 weeks, with up to 5 sessions weekly (each 3 hours long); approximately 1/3 carried out with a therapist, 2/3 completed independently at home or in clinic. | Typically delivered by an occupational therapist in clinic or hospital, with frequency and intensity tailored to patient ability, usually incorporating a range of functional and non-functional tasks under therapist supervision. |
| Evidence status | Evidence for sCIMT is currently limited to small single-group or early-phase clinical studies. Large randomized controlled data and real-world outcome evidence are not yet established. | Occupational therapy is supported by a broad base of randomized trials, systematic reviews, and guidelines showing benefit for motor recovery in eligible stroke survivors. |
| Important limitations | Small sample size, single-group design, and highly selected patient population limit generalizability. Effects beyond the short-term two-week intervention are not established. | Benefits may depend on therapy dose, frequency, patient adherence, and therapist experience; some patients with severe cognitive or motor impairment may gain less from standard therapy, highlighting variability in real-world effectiveness. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 2 weeks
Participants take part in the self-supervised constraint-induced movement therapy program. This includes up to 30 hours of rehabilitation over 2 weeks with sessions up to 5 times per week, combining therapist-guided training and independent exercises while wearing a mitt on the stronger hand.
Up to 5 sessions per week
Duration - Within 1 week after treatment
Participants complete tests and surveys within one week after finishing the therapy program to measure changes in arm and hand function, quality of life, and experiences with the therapy.
1 visit (in-person or remote)
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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https://pubmed.ncbi.nlm.nih.gov/22436358/Ohio State University
Lead Sponsor