Actively Recruiting
Sleep-dependent Learning in Aging
Led by University of Massachusetts, Amherst · Updated on 2025-04-03
584
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory processing. To this end, the investigators will investigate changes in learning following intervals of sleep (overnight and nap) and wake in young and older adults.
CONDITIONS
Official Title
Sleep-dependent Learning in Aging
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-80 years
- Healthy sleeper
- No diagnosed sleep disorder
- No diagnosed neurodegenerative disorder
You will not qualify if you...
- Past diagnosis of any sleep disorder or evidence of sleep disorder by assessments and polysomnography (Apnea-Hypopnea Index > 15; Period-Limb Movement in Sleep index > 15/hr; sleep-onset latency > 45 min; sleep efficiency < 80%)
- Past diagnosis of neurological illness or head injury
- Average sleep per night less than 5 or more than 9 hours
- Current shift work or inability to maintain regular sleep schedule during week before testing
- Current use of psychotropic, recreational, or sleep-altering medications
- Daily caffeine intake over 4 cups
- Weekly alcohol intake over 10 cups
- Pregnancy or less than 12 months postpartum
- History of bipolar disorder, mania, or current depression with Beck Depression Inventory score over 25
- Abnormal sleep due to shift work or travel across more than 2 time zones in past 3 months
- Diagnosis of any Axis I disorder, neurological illness, or head injury
- Cognitive dysfunction with subtest scores less than 40
- Beck Depression Scale score over 19
- For MRI studies (Experiments 1 and 4): left handed or ambidextrous, claustrophobia, presence of metal, pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Massachusetts
Amherst, Massachusetts, United States, 01003
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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