Actively Recruiting

Phase Not Applicable
Age: 18Years - 120Years
All Genders
Healthy Volunteers
NCT05237258

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Led by Massachusetts General Hospital · Updated on 2025-07-25

2300

Participants Needed

20

Research Sites

356 weeks

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

P

Patient-Centered Outcomes Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research study is evaluating whether primary palliative care is an alternative strategy to specialty palliative care for improving quality of life, symptoms, mood, coping, and end of life outcomes in patients with acute myeloid leukemia (AML).

CONDITIONS

Official Title

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Who Can Participate

Age: 18Years - 120Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Hospitalized patients aged 18 years or older with high-risk AML, including new diagnosis at age 60 or older, antecedent hematologic disorder, therapy-related disease, relapsed or primary refractory AML
  • Within five business days of starting intensive chemotherapy or hypomethylating agents treatment
  • Adult caregivers (18 years or older) who live with or have in-person contact at least twice per week with the patient
Not Eligible

You will not qualify if you...

  • Diagnosis of acute promyelocytic leukemia (APML)
  • Receiving supportive care alone for AML
  • Psychiatric or cognitive conditions preventing informed consent or compliance
  • Seen by a palliative care clinician during two previous hospitalizations in the past six months
  • Expected to be discharged within 2 days

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 20 locations

1

University of Alabama - Birmingham

Birmingham, Alabama, United States, 35294

Actively Recruiting

2

Stanford University

Stanford, California, United States, 94305

Actively Recruiting

3

University of Colorado Denver I Anschutz Medical Campus

Denver, Colorado, United States, 80204

Actively Recruiting

4

University of Miami

Miami, Florida, United States, 33146

Actively Recruiting

5

Moffitt Cancer Center

Tampa, Florida, United States, 33612

Actively Recruiting

6

Emory University

Atlanta, Georgia, United States, 30322

Actively Recruiting

7

Northwestern University

Evanston, Illinois, United States, 60208

Actively Recruiting

8

Indiana University

Bloomington, Indiana, United States, 47405

Actively Recruiting

9

Johns Hopkins University

Baltimore, Maryland, United States, 21218

Actively Recruiting

10

Massachusetts General Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

11

Dana-Farber Cancer Institute

Boston, Massachusetts, United States, 02215

Actively Recruiting

12

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

13

University of Rochester

Rochester, New York, United States, 14627

Actively Recruiting

14

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, United States, 27599

Actively Recruiting

15

Duke University

Durham, North Carolina, United States, 27708

Actively Recruiting

16

Ohio State University

Columbus, Ohio, United States, 43210

Actively Recruiting

17

Oregon Health & Science University

Portland, Oregon, United States, 97239

Actively Recruiting

18

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

19

Fred Hutchinson Cancer Center

Seattle, Washington, United States, 98109

Actively Recruiting

20

University of Wisconsin

Madison, Wisconsin, United States, 53715

Actively Recruiting

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Research Team

A

Areej El-Jawahri, MD

CONTACT

C

Chardria S Trotter, MPH, MBA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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