Actively Recruiting

Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT07345481

Stimulus Equivalence Learning in Acquired Brain Injury.

Led by Klimmendaal Revalidatiespecialisten · Updated on 2026-01-15

40

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

Sponsors

K

Klimmendaal Revalidatiespecialisten

Lead Sponsor

D

Donders Centre for Cognitive Neuroimaging

Collaborating Sponsor

AI-Summary

What this Trial Is About

Stimulus Equivalence Learning (SEL) is a form of learning in which stimuli (such as words, pictures, or sounds) become linked to one another in memory, even though this specific connection has not been directly taught. In a typical SEL task, two relations are taught explicitly (A→B and A→C), and the untrained relation (B→C) is then tested. This indirect relation is not intentionally or consciously learned and is considered a form of implicit learning. The principle of stimulus equivalence learning is still rarely applied in cognitive rehabilitation after acquired brain injury (ABI), with the exception of a few small (N=1) treatment studies that have shown positive effects. However, it remains unclear to what extent ABI may affect the ability to acquire stimulus equivalence.

CONDITIONS

Official Title

Stimulus Equivalence Learning in Acquired Brain Injury.

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults with acquired brain injury (ABI) more than 3 months post-injury, including stroke, traumatic brain injury, brain tumor, encephalitis, and out-of-hospital cardiac arrest (OHCA)
Not Eligible

You will not qualify if you...

  • Neurodegenerative disorders
  • Severe psychiatric disorders including suicidality
  • Insufficient command of the Dutch language
  • Severe cognitive impairments, aphasia, or visual or hearing problems that prevent test participation
  • For controls, any medical condition causing cognitive impairment beyond normal aging, including stroke, TBI, brain tumor, or other brain injury

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Klimmendaal Revalidatiespecialisten

Arnhem, Gelderland, Netherlands, 6813 GG

Actively Recruiting

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Research Team

E

Edo Grevers, MSc.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Stimulus Equivalence Learning in Acquired Brain Injury. | DecenTrialz