Actively Recruiting
A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving Filsuvez
Led by Amryt Pharma · Updated on 2025-09-19
580
Participants Needed
5
Research Sites
397 weeks
Total Duration
On this page
Sponsors
A
Amryt Pharma
Lead Sponsor
C
Chiesi Farmaceutici S.p.A.
Collaborating Sponsor
AI-Summary
What this Trial Is About
In patients with epidermolysis bullosa (EB), collagen does not form properly, so their skin is very fragile and blisters easily. Such patients are also at greatly increased risk of developing skin cancers. Filsuvez is a topical gel used to promote healing of skin lesions in patients with certain types of EB. In this observational study, patients with either dystrophic EB (DEB) or junctional EB (JEB) will receive standard of care treatment, whether Filsuvez or something else, and will be followed for up to 5 years. The main purpose is to see if the use of Filsuvez affects the likelihood of developing skin malignancies in these patient populations.
CONDITIONS
Official Title
A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving Filsuvez
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a confirmed diagnosis of dystrophic EB or junctional EB
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
CHU de Toulouse, Hôpital Larrey
Toulouse, France
Actively Recruiting
2
Hospital of Skin and Venereal Diseases of Thessaloniki
Thessaloniki, Greece
Actively Recruiting
3
Hospital Clinic, Barcelona
Barcelona, Spain
Actively Recruiting
4
Hospital San Juan de Dios (Barcelona)
Barcelona, Spain
Actively Recruiting
5
Guy's and St Thomas' NHS Foundation Trust
London, United Kingdom
Actively Recruiting
Research Team
C
Chiesi Clinical Trials
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here