Brazilian Multicenter Study Following Adults with Severe and Very Severe COPD for One Year

What this Trial Is About

Researchers are conducting an observational, prospective, multicenter cohort study to evaluate patients with severe and very severe Chronic Obstructive Pulmonary Disease COPD in Brazil. The study focuses on patients classified according to the GOLD 2024 guidelines, exploring how COPD severity relates to exacerbation rates, disease progression, complications, and mortality. This study aims to provide national data on this specific subgroup of COPD patients across different Brazilian regions with varying environmental exposures and genetic backgrounds. This non-interventional study will include patients from eight medical centers representing all five regions of Brazil, including teaching and tertiary hospitals. Participants will be enrolled consecutively and followed for 12 months. The study involves on-site visits at enrollment, 6 months, and 12 months, with tele-consults at 3 and 9 months to collect clinical data, especially regarding exacerbations. Participants will undergo evaluations during scheduled visits and tele-consults, with data collected and reviewed by the studys adjudication team. Researchers will measure outcomes such as the incidence of hospitalizations, exacerbations, mortality, vaccination rates, and lung neoplasia over approximately one year. The study emphasizes gathering comprehensive clinical information through direct and remote contacts to understand COPD progression and related health events.

Study That Will Evaluate the Brazilian Population With COPD.