Completed

Phase 2
Age: 18Years +
All Genders
ID00000925

Evaluation of High Protein Supplementation in HIV-1-Positive Subjects With Stable Weight Loss

Led by National Institute of Allergy and Infectious Diseases (NIAID) · Updated on 2013-07-29

56

Participants Needed

19

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to determine whether a high-quality protein food supplement will help HIV-positive patients maintain, and possibly gain, muscle mass. Many HIV-positive patients lose weight that they are then unable to regain. This may be because patients are not eating enough protein or are not eating the right kinds of protein. The protein eaten in foods (such as meat, eggs, or beans) may not be able to make up for the amount of protein lost due to HIV infection. This study gives patients high-quality protein food supplements to help them maintain and/or gain weight.

CONDITIONS

Official Title

A Study to Evaluate High Protein Supplementation in HIV-Positive Patients With Stable Weight Loss

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

Inclusion Criteria

You may be eligible for this study if you:

  • Are HIV-positive.
  • Are at least 18 years old.
  • Have an HIV level less than 5,000 copies/ml within 30 days of study entry.
  • Have lost weight in the past year, but your weight has remained fairly stable in the 2 months prior to enrollment.
  • Are expected to live for at least 6 months.
  • Are usually able to eat enough to maintain your present weight.
  • Are able to complete a 3-day food diary.

Exclusion Criteria

You will not be eligible for this study if you:

  • Have gained a significant amount of weight in the past 2 months.
  • Have any opportunistic (HIV-associated) infections.
  • Are unable to eat enough food for any reason, or are on tube feeding.
  • Have nausea, diarrhea, or vomiting in the 14 days prior to study entry.
  • Are being treated for diabetes.
  • Are receiving chemotherapy or radiation therapy to treat cancer.
  • Are pregnant or breast-feeding.
  • Are allergic to milk or mangoes.
  • Have an implanted defibrillator.
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

Trial Site Locations

Total: 19 locations

1

Univ of Southern California / LA County USC Med Ctr

Los Angeles, California, United States, 900331079

Status Unknown

2

UCLA CARE Ctr

Los Angeles, California, United States, 90095

Status Unknown

3

San Francisco Gen Hosp

San Francisco, California, United States, 941102859

Status Unknown

4

Stanford Univ Med Ctr

Stanford, California, United States, 943055107

Status Unknown

5

Univ of Colorado Health Sciences Ctr

Denver, Colorado, United States, 80262

Status Unknown

6

Queens Med Ctr

Honolulu, Hawaii, United States, 96816

Status Unknown

7

Univ of Hawaii

Honolulu, Hawaii, United States, 96816

Status Unknown

8

Tulane Univ School of Medicine

New Orleans, Louisiana, United States, 70112

Status Unknown

9

Johns Hopkins Hosp

Baltimore, Maryland, United States, 21287

Status Unknown

10

St Louis Regional Hosp / St Louis Regional Med Ctr

St Louis, Missouri, United States, 63112

Status Unknown

11

Chelsea Ctr

New York, New York, United States, 10021

Status Unknown

12

Cornell Univ Med Ctr

New York, New York, United States, 10021

Status Unknown

13

Univ of Rochester Medical Center

Rochester, New York, United States, 14642

Status Unknown

14

Univ of Cincinnati

Cincinnati, Ohio, United States, 452670405

Status Unknown

15

Ohio State Univ Hosp Clinic

Columbus, Ohio, United States, 432101228

Status Unknown

16

Philadelphia Veterans Administration Med Ctr

Philadelphia, Pennsylvania, United States, 19104

Status Unknown

17

Julio Arroyo

West Columbia, South Carolina, United States, 29169

Status Unknown

18

Univ of Washington

Seattle, Washington, United States, 98104

Status Unknown

19

Univ of Puerto Rico

San Juan, Puerto Rico, 009365067

Status Unknown

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

0

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