Actively Recruiting

Phase 3
Age: 18Years +
All Genders
ID06935357

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Felzartamab Infusions in Adults With Immunoglobulin A Nephropathy (IgAN)

Led by Biogen · Updated on 2026-05-27

454

Participants Needed

239

Research Sites

105 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying the use of felzartamab for adults with Immunoglobulin A nephropathy (IgAN), a kidney disease caused by buildup of abnormal IgA antibodies that damage kidney filters. The study aims to understand how felzartamab affects proteinuria, or protein in the urine, as well as kidney function, safety, and how the body processes the drug. This research is a Phase 3 randomized, double-blind, placebo-controlled trial. Participants will be randomly assigned to receive either felzartamab or a placebo through intravenous infusions during a 24-week treatment period. Some participants with lower kidney function will receive treatment in separate cohorts. After treatment, there is an 80-week follow-up period. In total, participants will have 17 study visits over about two years. During the study, researchers will measure changes in urine protein levels, kidney filtration rates, and other clinical endpoints. They will also monitor felzartamab levels in the blood, immune responses, and any adverse events. Safety assessments include vital signs, lab tests, ECGs, and physical exams. The study tracks participants closely throughout treatment and follow-up to evaluate felzartamab's effects on IgAN.

CONDITIONS

Brief Title

A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Biopsy-confirmed diagnosis of IgAN within the past 10 years, or within 24 months if participant has type 2 diabetes
  • Estimated glomerular filtration rate (eGFR) of at least 30 mL/min/1.73 m² at screening; eGFR between 20 and less than 30 mL/min/1.73 m² allowed for certain cohorts
  • Proteinuria of 1.0 gram per day or higher, or urine protein:creatinine ratio (UPCR) of at least 0.8 g/g
  • Clinically stable on maximum tolerated or approved doses of ACE inhibitors, ARBs, or other approved kidney medications for at least 12 weeks before screening
  • Stable doses of these medications must be maintained throughout the study except for changes due to adverse events
  • Participants using dual endothelin angiotensin receptor antagonist (DEARA) cannot use ACE inhibitors or ARBs simultaneously
Not Eligible

You will not qualify if you...

  • History of secondary forms of IgAN linked to other systemic diseases
  • History of rapidly progressive IgAN with eGFR loss over 50% in 3 months not explained by other factors
  • IgAN with minimal change disease variant
  • Other progressive glomerulonephritis or non-immunologic kidney diseases like diabetic nephropathy
  • Type 2 diabetes with HbA1c over 8% or evidence of diabetic complications
  • Diagnosed or suspected immunosuppressed or immunodeficient conditions, except corneal transplants
  • Use of immunosuppressive or immunomodulatory drugs within 4 months before screening, except stable hydroxychloroquine in Mainland China
  • Use of oral budesonide within 4 months prior to screening
  • Active or recurrent significant infections or recent IV anti-infective treatment
  • Low serum Immunoglobulin G (IgG) below 6.0 g/L at screening
  • Other protocol-defined exclusion criteria may apply

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Up to 36 weeks

Participants receive several intravenous (IV) doses of felzartamab or placebo to evaluate the effects on proteinuria and kidney function in Immunoglobulin A nephropathy (IgAN).

Multiple IV infusion visits and follow-up assessments during treatment period

Follow-up

Duration - Up to 68 weeks after treatment

Participants are monitored for changes in kidney function and safety outcomes after completing treatment, including assessments up to Week 104.

Periodic visits for monitoring up to Week 104

Trial Site Locations

Total: 239 locations

1

Applied Research Center of Arkansas

Little Rock, Arkansas, United States, 72205

Actively Recruiting

2

Kidney & Hypertension Center - Apple Valley

Apple Valley, California, United States, 92307

Actively Recruiting

3

Scripps Green Hospital

Carlsbad, California, United States, 92009

Actively Recruiting

4

National Institute of clinical Research Administration Office

Garden Grove, California, United States, 92844-2751

Withdrawn

5

UCLA Health David Geffen School of Medicine

Los Angeles, California, United States, 90095

Actively Recruiting

6

FOMAT Medical Research - FOMAT - PPDS

Oxnard, California, United States, 93030

Actively Recruiting

7

North America Research Institute-San Dimas

San Dimas, California, United States, 91773

Actively Recruiting

8

Nova Clinical Research, LLC

Bradenton, Florida, United States, 34209

Actively Recruiting

9

University of Florida - Gainesville - 1600 SW Archer Rd

Gainesville, Florida, United States, 32610

Not Yet Recruiting

10

Royal Research, Corp.

Hollywood, Florida, United States, 33024

Actively Recruiting

11

Central Florida Kidney Specialists

Orlando, Florida, United States, 32806

Actively Recruiting

12

CDC Research Institute, LLC

Port Saint Lucie, Florida, United States, 34952

Actively Recruiting

13

American Clinical Trials LLC

Acworth, Georgia, United States, 30101

Withdrawn

14

The Vasculitis and Glomerulonephritis Center at Massachusetts General Hospital

Boston, Massachusetts, United States, 02114-4724

Actively Recruiting

15

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115-6110

Actively Recruiting

16

UMass Memorial Medical Center

Worcester, Massachusetts, United States, 01655

Not Yet Recruiting

17

Henry Ford Hospital

Detroit, Michigan, United States, 48202

Actively Recruiting

18

Elixia Health - Michigan Kidney Consultants, LLC - Elixia - PPDS

Pontiac, Michigan, United States, 48341

Withdrawn

19

Anointed Nephrology and HTN - SKYCRNG - PPDS

Brookhaven, Mississippi, United States, 39601

Actively Recruiting

20

Midwest Nephrology Associates,Inc.

City of Saint Peters, Missouri, United States, 63376

Withdrawn

21

Icahn School of Medicine at Mount Sinai

New York, New York, United States, 10029-6504

Not Yet Recruiting

22

James J Peters Veterans Administration Medical Center - NAVREF - PPDS

The Bronx, New York, United States, 10468

Actively Recruiting

23

Penn Renal Electrolyte and Hypertension Perelman

Philadelphia, Pennsylvania, United States, 19104

Not Yet Recruiting

24

Lifespan at Rhode Island Hospital

Providence, Rhode Island, United States, 02903

Actively Recruiting

25

Knoxville Kidney Center, PLLC

Knoxville, Tennessee, United States, 37923-3624

Actively Recruiting

26

Texas Kidney Institute - Dallas

Dallas, Texas, United States, 95231

Actively Recruiting

27

Provecta Research Network

Houston, Texas, United States, 77054

Actively Recruiting

28

R & H Clinical Research

Katy, Texas, United States, 77974

Actively Recruiting

29

Hospital Italiano de Buenos Aires

Almagro, Ciudad Autónoma de BuenosAires, Argentina, C1199ABB

Actively Recruiting

30

INECO Neurociencias Oroño

Rosario, Santa Fe Province, Argentina, 2000

Actively Recruiting

31

CIMER-Centro Integral de Medicina Respiratoria

San Miguel de Tucumán, Tucumán Province, Argentina, T4000CBC

Actively Recruiting

32

Consultorios Médicos Dr. Doreski - Fundacion Respirar - PPDS

Buenos Aires, Argentina, B1605

Actively Recruiting

33

DOM Centro de Reumatología

Buenos Aires, Argentina, C1111AAH

Actively Recruiting

34

Maffei Centro Médico

Buenos Aires, Argentina, C1425

Not Yet Recruiting

35

Clínica de Nefrología Urología Y Enfermedades Cardiovasculares

Santa Fe, Argentina, 3000

Not Yet Recruiting

36

John Hunter Hospital

New Lambton, New South Wales, Australia, 2305

Actively Recruiting

37

Concord Repatriation General Hospital

New South Wales, New South Wales, Australia, 2060

Actively Recruiting

38

Westmead Hospital

Westmead, New South Wales, Australia, 2145

Actively Recruiting

39

Townsville Hospital

Douglas, Queensland, Australia, 4814

Actively Recruiting

40

Gold Coast University Hospital

Southport, Queensland, Australia, 4215

Actively Recruiting

41

Griffith University

Southport, Queensland, Australia, 4222

Actively Recruiting

42

Sunshine Hospital - Australia

St Albans, Victoria, Australia, 3021

Actively Recruiting

43

Hôpital Erasme - PPDS

Anderlecht, Brussels Capital, Belgium, 1070

Actively Recruiting

44

ZOL Genk - campus Sint-Jan

Genk, Limburg, Belgium, 3600

Not Yet Recruiting

45

UZ Leuven - PPDS

Leuven, Vlaams Brabant, Belgium, 3000

Actively Recruiting

46

Jan Yperman

Ieper, West-Vlaanderen, Belgium, 8900

Actively Recruiting

47

AZ Groeninge

Kortrijk, West-Vlaanderen, Belgium, 8500

Actively Recruiting

48

Cliniques Universitaires Saint-Luc

Brussels, Belgium, 1200

Actively Recruiting

49

Freire Pesquisa Clínica

Belo Horizonte, Minas Gerais, Brazil, 30150-320

Actively Recruiting

50

Irmandade da Santa Casa de Misericórdia de Belo Horizonte - PPDS

Belo Horizonte, Minas Gerais, Brazil, 30150221

Actively Recruiting

51

Centro Mineiro de Pesquisa - CMiP

Juiz de Fora, Minas Gerais, Brazil, 36010

Actively Recruiting

52

Fundação Universidade de Caxias do Sul - Instituto de Pesquisas em Saúde

Caxias do Sul, Rio Grande do Sul, Brazil, 95070-560

Actively Recruiting

53

Hospital de Clinicas de Porto Alegre (HCPA) - PPDS

Porto Alegre, Rio Grande do Sul, Brazil, 90035-903

Actively Recruiting

54

Hospital Alemao Oswaldo Cruz- HAOC

São Paulo, Brazil, 01323-903

Actively Recruiting

55

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

São Paulo, Brazil, 05403-000

Actively Recruiting

56

Medical Center Medconsult Pleven - Lovech Branch

Lovech, Bulgaria, 5500

Actively Recruiting

57

Medical Center Hera EOOD, Montana - Hera Clinics - PPDS

Montana, Bulgaria, 3400

Actively Recruiting

58

Medical Center Medconsult Pleven OOD

Pleven, Bulgaria, 5800

Actively Recruiting

59

University Multiprofile Hospital for Active Treatment Sv Ivan Rilski EAD-15 Acad. Ivan Geshov Blvd

Sofia, Bulgaria, 1606

Actively Recruiting

60

St Paul's Hospital

Vancouver, British Columbia, Canada, V6Z 1Y6

Not Yet Recruiting

61

McGill University Health Centre (MUHC)

Montreal, Quebec, Canada, H4A3J1

Actively Recruiting

62

Fu Yang People's Hospital - South Campus

Fuyang, Anhui, China, 236000

Actively Recruiting

63

The First Affiliated Hospital of Anhui Medical University - Jixilu Campus

Hefei, Anhui, China, 230022

Actively Recruiting

64

Peking University First Hospital - Changqiao Campus

Beijing, Beijing Municipality, China, 100034

Actively Recruiting

65

Beijing Tsinghua Changgung Hospital

Beijing, Beijing Municipality, China, 102218

Actively Recruiting

66

Fujian Medical University Union Hospital

Fuzhou, Fujian, China, 350001

Actively Recruiting

67

Zhongshan Hospital Xiamen University

Xiamen, Fujian, China, 361004

Actively Recruiting

68

Gansu Provincial Hospital

Lanzhou, Gansu, China, 730000

Actively Recruiting

69

The First Affiliated Hospital of Guangzhou Medical University - Yanjiang Campus

Guangzhou, Guangdong, China, 510120

Actively Recruiting

70

Shenzhen Hospital of Southern Medical University

Shenzhen, Guangdong, China, 510086

Actively Recruiting

71

Peking University Shenzhen Hospital

Shenzhen, Guangdong, China, 518036

Actively Recruiting

72

Zhongshan Hospital of Traditional Chinese Medicine

Zhongshan, Guangdong, China, 528401

Actively Recruiting

73

The First Affiliated Hospital of Guangxi Medical University

Nanning, Guangxi, China, 530021

Actively Recruiting

74

The People's Hospital of Guangxi Zhuang Autonomous Region

Nanning, Guangxi, China, 530021

Actively Recruiting

75

The Affiliated Hospital of Guizhou Medical University

Guiyang, Guizhou, China, 550000

Actively Recruiting

76

Cangzhou Central Hospital

Cangzhou, Hebei, China, 61011

Actively Recruiting

77

The Second Hospital of Hebei Medical University - Main

Shijiazhuang, Hebei, China, 50000

Actively Recruiting

78

The Third Hospital of Hebei Medical University

Shijiazhuang, Hebei, China, 50000

Actively Recruiting

79

Daqing Oilfield General Hospital

Daqing, Heilongjiang, China, 163001

Actively Recruiting

80

The First Affiliated Hospital of Henan Science and Technology University - Jinghua Campus

Luoyang, Henan, China, 471003

Actively Recruiting

81

Queen Mary Hospital PPDS

Hong Kong, Hong Kong, China, 999077

Actively Recruiting

82

Yichang Central People's Hospital - Wujiagang Campus

Yichang, Hubei, China, 443003

Actively Recruiting

83

The Second Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210011

Actively Recruiting

84

Affiliated Hospital of Nantong University

Nantong, Jiangsu, China, 226001

Actively Recruiting

85

Wuxi Peoples Hospital

Wuxi, Jiangsu, China, 214023

Actively Recruiting

86

Qilu Hospital of Shandong University

Jinan, Shandong, China, 250012

Actively Recruiting

87

The Second Hospital of Shandong University

Jinan, Shandong, China, 250033

Actively Recruiting

88

Yantai Yuhuangding Hospital

Yantai, Shandong, China, 264000

Not Yet Recruiting

89

Zhongshan Hospital Fudan University

Shanghai, Shanghai Municipality, China, 200023

Actively Recruiting

90

Shanghai General Hospital - North Campus

Shanghai, Shanghai Municipality, China, 200080

Actively Recruiting

91

Jiading Central Hospital

Shanghai, Shanghai Municipality, China, 201899

Actively Recruiting

92

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital

Chengdu, Sichuan, China, 610072

Actively Recruiting

93

Jinhua Municipal Central Hospital

Jinhua, Zhejiang, China, 321000

Actively Recruiting

94

Taizhou Hospital of Zhejiang Province - Main

Taizhou, Zhejiang, China, 317000

Actively Recruiting

95

Clinica de la Costa S.A.S. - PPDS

Barranquilla, Atlántico, Colombia, 80020

Not Yet Recruiting

96

Hospital Universitario San Ignacio

Bogotá, Cundinamarca, Colombia, 110231

Not Yet Recruiting

97

Healthy Medical Center S.A.S.

Zipaquirá, Cundinamarca, Colombia, 250252

Not Yet Recruiting

98

Fundacion Valle Del Lili

Cali, Valle del Cauca Department, Colombia, 760032

Not Yet Recruiting

99

Klinicki bolnicki centar Sestre Milosrdnice - Vinogradska cesta 29

Zagreb, City of Zagreb, Croatia, 10000

Actively Recruiting

100

Polyclinic Bonifarm

Zagreb, City of Zagreb, Croatia, 10000

Actively Recruiting

101

Clinical Hospital Center Rijeka

Rijeka, Croatia, 51000

Actively Recruiting

102

Special Hospital Medico

Rijeka, Croatia, 51000

Actively Recruiting

103

Institut klinicke a experimentalni mediciny

Prague, Praha, Hlavní Mesto, Czechia, 140 21

Actively Recruiting

104

CHU de Strasbourg - Nouvel Hôpital Civil

Strasbourg, Bas-Rhin, France, 67091

Actively Recruiting

105

CHU de Besançon

Besançon, Dobus, France, 25000

Actively Recruiting

106

CHU de Bordeaux - Hôpital Pellegrin

Bordeaux, Gironde, France, 33076

Actively Recruiting

107

CHU de Reims - Hôpital Maison Blanche

Reims, Grand Est, France, 51092

Actively Recruiting

108

GHRMSA - Hôpital Emile Muller

Mulhouse, Haut-Rhin, France, 68100

Actively Recruiting

109

Hopital Foch

Suresnes, Hauts-de-Seine, France, 92150

Actively Recruiting

110

CHRU d'Orleans- Hôpital de La Source

Orléans, Loiret, France, 45067

Actively Recruiting

111

CHU de Nîmes - Hopital Universitaire Caremeau

Nîmes Cédex 9, Occitanie, France, 30929

Actively Recruiting

112

AP-HP - Hôpital Henri Mondor

Créteil, Val-de-Marne, France, 94000

Actively Recruiting

113

Centre Hospitalier Departemental de Vendee

La Roche-sur-Yon, Vendée, France, 85925

Actively Recruiting

114

CHU Amiens Picardie - Site Sud

Dreuil-lès-Amiens, France, 80470

Actively Recruiting

115

AP-HP - Hôpital Saint-Louis

Paris, France, 75010

Actively Recruiting

116

AP-HP - Hopital Tenon

Paris, France, 75020

Actively Recruiting

117

Nephrologisches Zentrum Villingen-Schwenningen

Villingen-Schwenningen, Baden-Wurttemberg, Germany, 78052

Actively Recruiting

118

Universitätsklinikum Frankfurt, Apotheke Haus 19

Frankfurt am Main, Hesse, Germany, 60596

Actively Recruiting

119

Universitätsmedizin der Johannes Gutenberg-Universität Mainz

Mainz, Rhineland-Palatinate, Germany, 55131

Actively Recruiting

120

Universitätsklinikum Carl Gustav Carus an der TU Dresden

Dresden, Saxony, Germany, 1307

Actively Recruiting

121

Charité - Universitätsmedizin Berlin

Berlin, Germany, 10117

Actively Recruiting

122

University General Hospital of Patras

Pátrai, Achaïa, Greece, 26500

Actively Recruiting

123

General Hospital of Athens ''G. Gennimatas''

Athens, Attica, Greece, 115 27

Actively Recruiting

124

General Hospital of Athens ''Hippokratio''

Athens, Attica, Greece, 115 27

Actively Recruiting

125

Laiko General Hospital of Athens

Athens, Attica, Greece, 11527

Actively Recruiting

126

University General Hospital ''ATTIKON'' - General Hospital of West Attica H AGIA VARVARA

Chaïdári, Attica, Greece, 12462

Actively Recruiting

127

General Hospital of Heraklion Venizeleio

Heraklion, Irakleio, Greece, 714 09

Actively Recruiting

128

PAGNI-University General Hospital of Heraklion

Heraklion, Irakleio, Greece, 715 00

Actively Recruiting

129

University General Hospital of Ioannina

Ioannina, Greece, 34098

Actively Recruiting

130

AHEPA University General Hospital of Thessaloniki

Thessaloniki, Greece, 54636

Actively Recruiting

131

Osmania General Hospital

Hyderabad, Andhra Pradesh, India, 500012

Actively Recruiting

132

Nizams Institute of Medical Sciences

Hyderabad, Andhra Pradesh, India, 500082

Actively Recruiting

133

All India Institute of Medical Sciences ( AIIMS ) - Raipur

Raipur, Chhattisgarh, India, 492099

Actively Recruiting

134

Zydus Hospital

Ahmedabad, Gujarat, India, 380081

Actively Recruiting

135

Muljibhai Patel Society for Research in Nephro-Urology

Nadiād, Gujarat, India, 387001

Actively Recruiting

136

Manipal Hospital Bangalore

Bangalore, Karnataka, India, 560017

Actively Recruiting

137

M.S. Ramaiah Medical College and Hospital

Bangalore, Karnataka, India, 560054

Actively Recruiting

138

Government Medical College, Kozhikode

Kozhikode, Kerala, India, 673008

Actively Recruiting

139

Trivandrum Medical College Hospital

Trivandrum, Kerala, India, 695011

Not Yet Recruiting

140

Seth G S Medical College and K E M Hospital

Mumbai, Maharashtra, India, 400012

Actively Recruiting

141

Noble Hospital

Pune, Maharashtra, India, 411013

Actively Recruiting

142

Max Super Speciality Hospital - Saket

New Delhi, National Capital Territory of Delhi, India, 110017

Actively Recruiting

143

Sir Ganga Ram Hospital

New Delhi, National Capital Territory of Delhi, India, 110060

Actively Recruiting

144

King George Medical University

Lucknow, Uttar Pradesh, India, 226003

Actively Recruiting

145

Sanjay Gandhi Postgraduate Institute of Medical Sciences

Lucknow, Uttar Pradesh, India, 226014

Actively Recruiting

146

Nil Ratan Sircar Medical College and Hospital

Kolkata, West Bengal, India, 700014

Actively Recruiting

147

Postgraduate Institute of Medical Education & Research (PGIMER)

Chandigarh, India, 160012

Actively Recruiting

148

Azienda Ospedaliero Universitaria di Parma

Fontevivo, Emilia-Romagna, Italy, 43010

Actively Recruiting

149

AUSL Piacenza - Ospedale Guglielmo da Saliceto

Piacenza, Emilia-Romagna, Italy, 29121

Actively Recruiting

150

Azienda Sanitaria Universitaria Giuliano Isontina (ASUGI) - Ospedale di Cattinara

Trieste, Friuli Venezia Giulia, Italy, 34149

Actively Recruiting

151

IRCCS Azienda Ospedaliera Metropolitana - Ospedale Policlinico San Martino

Genoa, Liguria, Italy, 16132

Not Yet Recruiting

152

ASST degli Spedali Civili di Brescia - Spedali Civili di Brescia

Brescia, Lombardy, Italy, 25123

Actively Recruiting

153

Centro di Ricerche Cliniche per le Malattie Rare Aldo e Cele Daccò

Ranica, Lombardy, Italy, 24020

Actively Recruiting

154

IRCCS Istituto Clinico Humanitas

Rozzano, Lombardy, Italy, 20089

Not Yet Recruiting

155

Azienda Ospedaliero Universitaria Maggiore della Carità

Novara, Piedmont, Italy, 28100

Withdrawn

156

ASL Città di Torino - Ospedale San Giovanni Bosco

Turin, Piedmont, Italy, 10154

Actively Recruiting

157

Fujita Health University Hospital

Toyoake-shi, Aiti, Japan, 470-1192

Actively Recruiting

158

Hirosaki University Hospital

Hirosaki-shi, Aomori, Japan, 036-8563

Actively Recruiting

159

National Hospital Organization Chiba Medical Center Chibahigashi National Hospital

Chiba, Chiba, Japan, 260-8712

Actively Recruiting

160

Juntendo University Urayasu Hospital

Urayasu-Shi, Chiba, Japan, 279-0021

Actively Recruiting

161

Hokkaido University Hospital

Sapporo, Hokkaido, Japan, 060-8648

Actively Recruiting

162

Hospital of the University of Occupational and Environmental Health, Japan

Kitakyushu-shi, Hukuoka, Japan, 807-8556

Actively Recruiting

163

Fukushima Medical University Hospital

Fukushima, Hukusima, Japan, 960-1247

Actively Recruiting

164

Toranomon Hospital Kajigaya

Kawasaki-shi, Kanagawa, Japan, 213-0015

Actively Recruiting

165

Kitasato University Hospital

Sagamihara-shi, Kanagawa, Japan, 252-0375

Actively Recruiting

166

Yokohama City University Hospital

Yokohama, Kanagawa, Japan, 236-0004

Actively Recruiting

167

University Hospital, Kyoto Prefectural University of Medicine

Kyoto, Kyôto, Japan, 602-8566

Actively Recruiting

168

Tohoku Medical and Pharmaceutical University Hospital

Sendai, Miyagi, Japan, 983-8512

Actively Recruiting

169

Nara Medical University Hospital

Kashihara, Nara, Japan, 634-8522

Actively Recruiting

170

Kawasaki Medical School Hospital

Kurashiki, Okayama-ken, Japan, 701-0192

Actively Recruiting

171

Hamamatsu University Hospital

Hamamatsu, Sizouka, Japan, 431-3192

Actively Recruiting

172

Tokushima University Hospital

Tokushima, Tokushima, Japan, 770-8503

Actively Recruiting

173

The Jikei University West Medical Center

Ashikaga-Shi, Tokyo, Japan, 326-0843

Actively Recruiting

174

Juntendo University Hospital

Bunkyo-Ku, Tokyo, Japan, 113-8431

Actively Recruiting

175

Jikei University Hospital

Minato-ku, Tokyo, Japan, 105-8471

Actively Recruiting

176

Showa Medical University Hospital

Shinagawa-ku, Tokyo, Japan, 142-86666

Actively Recruiting

177

Ikeda Municipal Hospital

Ikeda-shi, Ôsaka, Japan, 563-8510

Actively Recruiting

178

Osaka University Hospital

Suita-shi, Ôsaka, Japan, 565-0871

Actively Recruiting

179

Hospital Tengku Ampuan Afzan

Kuantan, Pahang, Malaysia, 25100

Actively Recruiting

180

Hospital Raja Permaisuri Bainun

Perak, Pahang, Malaysia, 30450

Actively Recruiting

181

University Malaya Medical Centre

Lembah Pantai, WilayahPersekutuan KualaLumpur, Malaysia, 59100

Actively Recruiting

182

Auckland City Hospital

Auckland, New Zealand, 1023

Not Yet Recruiting

183

Aotearoa Clinical Trials Trust- Middlemore Hospital

Auckland, New Zealand, 2025

Actively Recruiting

184

Wellington Hospital

Wellington, New Zealand, 6021

Actively Recruiting

185

Norzel Medical and Diagnostic Clinic Foundation Corp.

Cebu City, Cebu, Philippines, 6000

Actively Recruiting

186

MCM Krakow - PRATIA - PPDS

Krakow, Lesser Poland Voivodeship, Poland, 30727

Actively Recruiting

187

SCM Clinic - Prywatny Szpital Specjalistyczny

Krakow, Lesser Poland Voivodeship, Poland, 31-559

Actively Recruiting

188

SPZOZ Centralny Szpital Kliniczny UM w Lodzi - ul. Pomorska 251

Lodz, Lódzkie, Poland, 92-213

Actively Recruiting

189

Uniwersyteckie Centrum Kliniczne w Gdansku - Debinki 7

Gdansk, Pomeranian Voivodeship, Poland, 80-952

Actively Recruiting

190

Twoja Przychodnia - Szczecinskie Centrum Medyczne

Szczecin, West Pomeranian Voivodeship, Poland, 71-434

Actively Recruiting

191

Uniwersytecki Szpital Kliniczny Nr 2 PUM w Szczecinie

Szczecin, Poland, 70-110

Actively Recruiting

192

ULS de Lisboa Ocidental, EPE - Hospital Santa Cruz

Carnaxide, Lisbon District, Portugal, 2790

Actively Recruiting

193

ULS de Gaia/Espinho, EPE - Unidade I

Vila Nova de Gaia, Lisbon District, Portugal, 4434-502

Actively Recruiting

194

ULS da Região de Aveiro, EPE - Hospital Infante D. Pedro

Aveiro, Portugal, 3814

Actively Recruiting

195

Centro Clínico Académico, Braga - Hospital de Braga

Braga, Portugal, 4710-243

Actively Recruiting

196

ULS de Coimbra, EPE - Hospitais da Universidade de Coimbra

Coimbra, Portugal, 3004-561

Actively Recruiting

197

ULS da Região de Leiria, EPE - Hospital de Santo André

Leiria, Portugal, 2410-197

Actively Recruiting

198

ULS da Arrábida, EPE - Hospital de São Bernardo

Setúbal, Portugal, 2910-446

Actively Recruiting

199

FDI Clinical Research

San Juan, Puerto Rico, 00927

Actively Recruiting

200

Pusan National University Hospital

Busan, Gwangyeogsi, South Korea, 49241

Actively Recruiting

201

Hallym University Sacred Heart Hospital

Anyang-si, Gyeonggido, South Korea, 14068

Actively Recruiting

202

Seoul National University Bundang Hospital

Seongnam-si, Gyeonggido, South Korea, 13620

Actively Recruiting

203

Ajou University Hospital

Suwon, Gyeonggido, South Korea, 16499

Actively Recruiting

204

Severance Hospital Yonsei University Health System

Seoul, Seoul Teugbyeolsi, South Korea, 3722

Actively Recruiting

205

Hanyang University Seoul Hospital

Seoul, Seoul Teugbyeolsi, South Korea, 4763

Actively Recruiting

206

Inje University Haeundae Paik Hospital

Busan, South Korea, 48108

Actively Recruiting

207

Seoul National University Hospital

Seoul, South Korea, 03080

Actively Recruiting

208

Samsung Medical Center

Seoul, South Korea, 6351

Actively Recruiting

209

Fundacio Puigvert

Viladecans, Barcelona, Spain, 8840

Actively Recruiting

210

Hospital del Mar

Barcelona, Catalonia, Spain, 8003

Actively Recruiting

211

Hospital Universitario A Coruña

A Coruña, Galicia, Spain, 15006

Actively Recruiting

212

Hospital Universitario Fundacion Alcorcon

Alcorcón, Madrid, Spain, 28922

Actively Recruiting

213

Hospital Universitario de Getafe

Getafe, Madrid, Spain, 10400

Actively Recruiting

214

Hospital Universitario Vall d'Hebron - PPDS

Barcelona, Spain, 8035

Actively Recruiting

215

Hospital General San Pedro de Alcantara

Cáceres, Spain, 10003

Actively Recruiting

216

Hospital Universitari de Girona Dr Josep Trueta

Girona, Spain, 17007

Actively Recruiting

217

Hospital Universitario Fundacion Jimenez Diaz

Madrid, Spain, 28040

Actively Recruiting

218

Hospital Universitario 12 de Octubre

Madrid, Spain, 28041

Actively Recruiting

219

Hospital Universitario Virgen Macarena

Seville, Spain, 41009

Actively Recruiting

220

Hospital Universitario Miguel Servet

Zaragoza, Spain, 50009

Actively Recruiting

221

National Cheng Kung University Hospital

Dawan, Taiwan, Province of China, Taiwan, 70403

Actively Recruiting

222

Far Eastern Memorial Hospital

New Taipei City, Taiwan, Province of China, Taiwan, 220216

Actively Recruiting

223

China Medical University Hospital - PPDS

Taichung, Taiwan, Province of China, Taiwan, 40447

Actively Recruiting

224

Mackay Memorial Hospital-Taipei branch

Taipei, Taiwan, Province of China, Taiwan, 104449

Actively Recruiting

225

Taipei Municipal Wanfang Hospital

Taipei, Taiwan, Province of China, Taiwan, 116081

Actively Recruiting

226

Chang Gung Memorial Hospital, Linkou

Taoyuan, Taiwan, Province of China, Taiwan, 33305

Actively Recruiting

227

Kaohsiung Medical University - Chung-Ho Memorial Hospital

Kaohsiung City, Taiwan, 807

Actively Recruiting

228

Taipei Medical University Shuang Ho Hospital

New Taipei City, Taiwan, 235041

Actively Recruiting

229

Kocaeli Universitesi Arastirma ve Uygulama Hastanesi

İzmit, Kocaeli, Turkey (Türkiye), 41380

Actively Recruiting

230

Ankara Bilkent Sehir Hastanesi

Ankara, Turkey, Turkey (Türkiye), 34899

Actively Recruiting

231

Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi

Istanbul, Turkey, Turkey (Türkiye), 34899

Actively Recruiting

232

Mehmet Akif Inan Egitim ve Arastirma Hastanesi

Sanliurfa, Turkey, Turkey (Türkiye), 63040

Actively Recruiting

233

Akdeniz University Medical Faculty

Antalya, Turkey (Türkiye), 7070

Actively Recruiting

234

Istanbul Universitesi - Cerrahpasa Cerrahpasa Tip Fakultesi Hastanesi

Istanbul, Turkey (Türkiye), 34098

Actively Recruiting

235

Erciyes Universitesi Tip Fakultesi Gevher Nesibe Hastanesi

Kayseri, Turkey (Türkiye), 38039

Actively Recruiting

236

Royal Preston Hospital - NWCRN- PPDS

Preston, Lancashire, United Kingdom, PR2 9HT

Actively Recruiting

237

Leicester General Hospital

Leicester, Leicestershire, United Kingdom, LE5 4PW

Actively Recruiting

238

Northern General Hospital

Sheffield, South Yorkshire, United Kingdom, S5 7AU

Actively Recruiting

239

Royal Stoke University Hospital

Stoke-on-Trent, Staffordshire, United Kingdom, ST4 6QG

Actively Recruiting

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Research Team

U

US Biogen Clinical Trial Center

G

Global Biogen Clinical Trial Center

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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Frequently Asked Questions

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