Pilot Study of a Dedicated MRI Scan to Improve Pancreatic Cancer Screening in High-Risk Adults

What this Trial Is About

Researchers are working to improve pancreatic cancer screening by developing a specialized MRI scan of the pancreas, called magnetic resonance pancreas MRP. This study focuses on people at high risk for pancreatic cancer, particularly those enrolled in the Memorial Sloan Kettering Pancreatic Tumor Registry, to detect cancer more effectively. The goal is to compare the new high-resolution MRP images with conventional MRCP scans over up to three years. Participants will undergo a single MRI of the abdomen without contrast using the new MRP technique. Additionally, an endoscopic ultrasound EUS will be performed either on the same day or within two weeks prior to the MRP. These procedures are diagnostic tests conducted to assess the pancreas more precisely in high-risk individuals. During the study, participants will be monitored for image quality between the novel MRP and traditional MRCP scans. They must have completed an MRI with MRCP without any pancreatic abnormalities and be scheduled for EUS as part of their surveillance. The study will track imaging outcomes for up to three years, with participants consenting to follow-up contact and being US residents. Participation involves completing these scans and allowing ongoing evaluation of image quality to improve pancreatic cancer detection.

A Study of Magnetic Resonance Imaging of the Pancreas for Cancer Screening