Actively Recruiting
Surgical Outcomes and Complications of Posterior Spinal Fusion in Adolescent Idiopathic Scoliosis
Led by Assiut University · Updated on 2025-07-30
25
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Adolescent idiopathic scoliosis (AIS) is the most common type of scoliosis, affecting 1-3% of adolescents worldwide and occurring mostly in females. It involves a sideways curvature of the spine of 10 degrees or more in children aged 10 to 18 years without an underlying cause. The exact cause is unknown but may involve genetic factors and uneven growth of the spine during rapid growth periods, leading to curve progression. Severe scoliosis can cause cosmetic problems, height loss, reduced lung function, and long-term spinal degeneration. Treatment options include observation, bracing, and surgery for curves over 40 degrees. This study focuses on evaluating the outcomes and complications of posterior spinal fusion surgery for AIS patients with moderate to severe curves between 40 and 70 degrees. Posterior surgery is widely used due to advances in technique and training, offering spine correction with less impact on lung function and better sagittal balance correction compared to anterior surgery. Eligible participants are adolescents aged 10 to 18 years with specific curve types and skeletal maturity, who are candidates for surgery due to rapid curve progression or functional limitations. Participants will be followed for two years after surgery. Researchers will assess height, thoracic symmetry, rib hump, the Cobb angle of spinal curvature, and patient satisfaction with surgical outcomes. These evaluations aim to measure the radiological correction and functional results of the posterior spinal fusion. The study involves clinical evaluations over time to monitor correction success and any complications from the surgery.
CONDITIONS
Brief Title
Surgical Outcomes and Complications of Posterior Spinal Fusion in Adolescent Idiopathic Scoliosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female adolescents aged 10 to 18 years diagnosed with adolescent idiopathic scoliosis
- Patients with Risser sign 4 and 5 indicating skeletal maturity
- Patients with Lenke classification system types 2, 3, or 4
- Spinal curvature between 40 and 70 degrees Cobb angle
- Candidates for surgical intervention due to rapid progression over 5 degrees per year or functional limitations
You will not qualify if you...
- Congenital or neuromuscular scoliosis
- Pre-operative restrictive lung function
- Previous spinal surgery
- Severe co-morbidities preventing surgical intervention
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 2 weeks or until discharge
Participants undergo posterior spinal fusion surgery followed by immediate post-operative care.
1 surgical visit and approximately 3 post-operative visits
Duration - Up to 2 years
Participants are monitored for surgical outcomes, complications, and recovery progress.
Regular follow-up visits over 2 years
Trial Site Locations
Total: 1 location
1
Assiut university hospitals
Asyut, Egypt, Egypt, 71515
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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