Actively Recruiting
SYSTEMS-LEVEL ANALYSES OF IMMUNE DYSREGULATION
Led by Karolinska Institutet · Updated on 2024-02-08
500
Participants Needed
1
Research Sites
417 weeks
Total Duration
On this page
Sponsors
K
Karolinska Institutet
Lead Sponsor
K
Karolinska University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of the SAID study is to create a national resource in Sweden to enable comprehensive immunological analyses of an extremely complex and clinically challenging group of individuals with variable forms of immune system dysregulation. We hope to establish a biobank of primarily blood and fecal samples from children and adults, with confirmed or suspected immune dysregulation, as well as age- and sex- matched healthy controls, for comparisons of immune cell/mediator alongside various clinical presentations of these immunological diseases as well as microbiome samples as possible a possible modifier of clinical presentations. The project will also include the establishment of a national database with deep immunological data, treatment and clinical outcomes for these patients, accessible to participating researchers and clinicians.
CONDITIONS
Official Title
SYSTEMS-LEVEL ANALYSES OF IMMUNE DYSREGULATION
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients of all ages seeking care or being referred for suspected immune dysregulation or with a known immune-mediated disease and failing to respond to standard therapy
You will not qualify if you...
- Healthy control individuals diagnosed with an immune-mediated disorder
- Healthy control individuals receiving immunomodulatory treatment
- Healthy control individuals with current infection
- Healthy control individuals with cancer
AI-Screening
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Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Karolinska Institutet
Stockholm, Sweden, SE171 77
Actively Recruiting
Research Team
P
Petter Brodin, M.D., Ph.D
CONTACT
G
Genia Kretzschmar, M.D
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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