Actively Recruiting
Taiwan Associated Genetic and Nongenetic Small Vessel Disease
Led by National Taiwan University Hospital · Updated on 2026-01-20
500
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The TAG-SVD enrolled patients with clinical and neuroimaging features of cerebral small vessel disease (CSVD). All enrolled patients will receive next-generation sequence (NGS) with probes designed to target five candidate CSVD genes, and patients will be divided into genetic or non-genetic groups accordingly. Their clinical features and outcome will be followed for at least 2 years.
CONDITIONS
Official Title
Taiwan Associated Genetic and Nongenetic Small Vessel Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must have at least one of the following symptoms or history: stroke (especially small vessel occlusion type of ischemic stroke, spontaneous intracerebral hemorrhage, or young stroke)
- Cognitive impairment or dementia
- Gait disturbance
- Parkinsonism (especially vascular parkinsonism features)
- Headache (especially migraine)
- Positive family history of hereditary cerebral small vessel disease
- MRI evidence of cerebral small vessel disease, including mild to moderate white matter hyperintensity, any lacune, or any cerebral microbleed
You will not qualify if you...
- MRI evidence of cerebral small vessel disease due to other inflammatory, malignancy, or structural lesions
- Patients or family members not willing to sign informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Neurology, National Taiwan University Hospital
Taipei, Taiwan, 100
Actively Recruiting
Research Team
S
Sung-Chun Tang, MD, PhD
CONTACT
C
Chih-Hao Chen, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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