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Actively Recruiting

Age: 6Months - 18Years
All Genders
ID04423484

Therapeutic Recommendations for the Treatment of Children With Nephroblastoma in Africa

Led by French Africa Pediatric Oncology Group · Updated on 2026-03-02

1000

Participants Needed

7

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate how well treatment units follow therapeutic recommendations for children diagnosed with Nephroblastoma, a type of kidney cancer. It builds on two previous studies by the French Africa Pediatric Oncology Group GFAOP and focuses on treatment compliance and outcomes for children receiving care. The study also seeks to assess improvements in treatment adherence and reporting to better tailor future treatment programs to local conditions. The study involves children with suspected Nephroblastoma who receive standard care while clinical data are collected. Researchers will gather information on the clinical stage, treatments given, any treatment-related side effects, outcomes after treatment, and follow-up care. This observational study does not involve experimental treatments but monitors how existing protocols are applied and their results over time. Participants will be followed for up to five years, during which data on disease stage at diagnosis, treatment details, and follow-up visits will be recorded. The primary outcomes include the number of cases with localized and advanced disease, treatment regimens used, and compliance with follow-up care. Secondary outcomes examine reasons for treatment failure. This long-term monitoring helps understand treatment effectiveness and areas for improvement in care delivery.

CONDITIONS

Brief Title

Therapeutic Recommendations for Nephroblastoma

Who Can Participate

Age: 6Months - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged between 6 months and 18 years
  • Diagnosed with unilateral Nephroblastoma (tumor in one kidney)
  • No prior treatment for Nephroblastoma
  • General health status allows for treatment
Not Eligible

You will not qualify if you...

  • Bilateral Nephroblastoma tumor (tumor in both kidneys)
  • Previous treatment for Nephroblastoma
  • Disease considered too advanced
  • Uncertain diagnosis of Nephroblastoma
  • Refusal of treatment

Research Team

B

BRENDA Ms MALLON, MSC

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