Actively Recruiting

All Genders
Healthy Volunteers
NCT02302742

Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry

Led by University of Kansas Medical Center · Updated on 2025-10-06

1500

Participants Needed

11

Research Sites

819 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

PROGECT is a registry for patients with Triple Negative breast cancer (TNBC) or patients who have an identified germline mutations (such as a mutation on the BRCA1 or BRCA2 genes).

CONDITIONS

Official Title

Triple Negative Breast Cancer and Germline Hereditary Breast and Ovarian Cancer Mutation Carrier Registry

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Triple Negative Breast Cancer (ER/PR <10% and HER2 negative) per ASCO/CAP guidelines
  • Stages I through IV of Triple Negative Breast Cancer
  • Any age at diagnosis
  • Diagnosis within the past 5 years
  • Eligible regardless of genetic testing status
  • Genetic testing recommended if meeting NCCN and Medicare guidelines
  • Carry deleterious or uncertain germline mutations in hereditary breast and ovarian cancer genes (BRCA, PTEN, P53, PALB2, etc) regardless of cancer type or site
  • Healthy carriers of these mutations are eligible
  • No time limit from cancer diagnosis to enrollment
  • Eligible regardless of personal cancer history
Not Eligible

You will not qualify if you...

  • Triple Negative Breast Cancer diagnosis more than 5 years ago
  • Carry only a hereditary breast and ovarian cancer mutation classified as a "polymorphism" or "favor polymorphism"

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 11 locations

1

Hays Medical Center Dreiling-Schmidt Cancer Institute

Hays, Kansas, United States, 67601

Actively Recruiting

2

KCCC West

Kansas City, Kansas, United States, 66112

Actively Recruiting

3

KCCC Overland Park

Overland Park, Kansas, United States, 66210

Actively Recruiting

4

Overland Park Regional Medical Center

Overland Park, Kansas, United States, 66215

Actively Recruiting

5

Salina Regional Health Center - Tammy Walker Cancer Center

Salina, Kansas, United States, 67401

Actively Recruiting

6

The University of Kansas Cancer Center

Westwood, Kansas, United States, 66205

Actively Recruiting

7

Universtiy Health

Kansas City, Missouri, United States, 64108

Actively Recruiting

8

KCCC South

Kansas City, Missouri, United States, 64131

Actively Recruiting

9

Research Medical Center

Kansas City, Missouri, United States, 64132

Actively Recruiting

10

KCCC - North

Kansas City, Missouri, United States, 64154

Actively Recruiting

11

KCCC Lee's Summit

Lee's Summit, Missouri, United States, 64064

Actively Recruiting

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Research Team

J

Joshua Staley

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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