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ID07454447

Ultrasound Biomicroscopy Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma

Led by Minia University Hospital · Updated on 2026-03-06

30

Participants Needed

1

Research Sites

4 weeks

Total Duration

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AI-Summary

What this Trial Is About

This research focuses on primary open-angle glaucoma, a chronic eye condition that often needs surgery when medications are not enough. It aims to study detailed ultrasound images of the eye's front part after a combined surgical procedure called deep sclerectomy with trabeculotomy. The study seeks to understand the anatomical changes after surgery and how they relate to patient outcomes. Patients who have undergone the combined deep sclerectomy with trabeculotomy surgery are observed using ultrasound biomicroscopy (UBM), a non-invasive imaging technique. UBM is used to examine the intrascleral lake, filtering bleb, and other eye structures after surgery. The study collects clinical data such as eye pressure and the number of glaucoma medications needed, correlating these with the UBM findings to identify predictors of surgical success. Participants will be evaluated at 3 and 6 months after surgery with UBM imaging and clinical assessments including intraocular pressure measurements and medication tracking. The study monitors anatomical and functional outcomes to better understand the effects of this combined surgery. The total participation includes postoperative follow-up visits for detailed imaging and clinical evaluation to assess safety and effectiveness.

CONDITIONS

Brief Title

UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of primary open-angle glaucoma (POAG), including juvenile open-angle glaucoma (JOAG)
  • Patients who underwent combined deep sclerectomy with trabeculotomy
  • Clear media allowing adequate ultrasound biomicroscopy imaging
  • Written informed consent obtained from the patient
Not Eligible

You will not qualify if you...

  • Secondary glaucomas such as neovascular, uveitic, traumatic, or angle-closure glaucoma
  • Previous glaucoma filtering surgery in the studied eye
  • Coexisting ocular pathology affecting ultrasound biomicroscopy assessment, including severe corneal opacity or scleral pathology

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Postoperative Monitoring

Duration - 6 months

Participants who underwent combined deep sclerectomy with trabeculotomy are observed postoperatively. Ultrasound biomicroscopy is used to evaluate anterior segment structures such as the intrascleral lake and filtering bleb morphology. Clinical parameters including intraocular pressure and number of antiglaucoma medications are recorded and correlated with imaging findings.

Visits at 3 and 6 months postoperatively

Trial Site Locations

Total: 1 location

1

Minia University Hospital

Minya, Minya Governorate, Egypt

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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