Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT07117227

Validation of RCC Predicting Model With Emulated-target Trial

Led by Peking University Third Hospital · Updated on 2026-04-14

4700

Participants Needed

1

Research Sites

99 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This single-center study utilizes real-world data (2012-2024) from 4700 renal cell carcinoma (RCC) patients at Peking University Third Hospital to: (1) Develop and validate a prognostic prediction model specifically for RCC patients, including those with venous tumor thrombus (VTT); (2) Compare the performance of this new model against existing RCC prediction models in both the overall RCC cohort and the VTT subgroup; (3) Employ an emulated target trial (ETT) methodology to evaluate whether risk-stratified treatment based on the prediction model (grouping patients as high/medium/low risk) improves survival outcomes .

CONDITIONS

Official Title

Validation of RCC Predicting Model With Emulated-target Trial

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 65 18 years of age
  • Diagnosis of primary renal cell carcinoma before and during the surgery
  • Received radical nephrectomy or nephron-sparing surgery
Not Eligible

You will not qualify if you...

  • Subjects with severely missing clinical information
  • History of other malignant tumors
  • Recurrence observed before first postoperative follow-up
  • Discontinued adjuvant treatment within first two courses due to severe adverse reactions

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University Third Hospital

Beijing, Beijing Municipality, China, 100191

Actively Recruiting

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Research Team

J

Jiyuan Chen, master

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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