Actively Recruiting

Age: 18Years +
All Genders
NCT05246345

Venetoclax Resistance Landscape in Chronic Lymphocytic Leukemia

Led by University Hospital, Clermont-Ferrand · Updated on 2024-01-09

50

Participants Needed

14

Research Sites

260 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to collect medical informations and samples from refractory and/or relapsed chronic lymphocytic leukemia during or after venetoclax treatment, in order to evaluate the frequency of resistance mechanisms.

CONDITIONS

Official Title

Venetoclax Resistance Landscape in Chronic Lymphocytic Leukemia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than or equal to 18 years old
  • Diagnosis of chronic lymphocytic leukemia according to iwCLL criteria
  • Refractory and/or relapsed disease during or after venetoclax treatment
  • Availability of tumor samples
  • Relapse may be progressive chronic lymphocytic leukemia or transformation into Richter syndrome
  • Ability to express opposition to enrollment if desired
  • Affiliation with the French Social Security system
Not Eligible

You will not qualify if you...

  • Patients or their legal guardians who refuse to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 14 locations

1

CHU d'Amiens

Amiens, France

Not Yet Recruiting

2

CHU de Besançon

Besançon, France

Not Yet Recruiting

3

Hopital AVICENNE

Bobigny, France

Not Yet Recruiting

4

CHU clermont-ferrand

Clermont-Ferrand, France

Not Yet Recruiting

5

CHU de Clermont Ferrand

Clermont-Ferrand, France

Not Yet Recruiting

6

CHU Grenoble

Grenoble, France

Not Yet Recruiting

7

CHRU de Lille

Lille, France

Not Yet Recruiting

8

Centre LEON BERARD

Lyon, France

Not Yet Recruiting

9

CHU de Montpellier

Montpellier, France

Not Yet Recruiting

10

CHU Nancy

Nancy, France

Not Yet Recruiting

11

Hopital Pitié Salpetrière

Paris, France

Not Yet Recruiting

12

Hopital Haut LEVEQUE

Pessac, France

Not Yet Recruiting

13

CHU de Reims

Reims, France

Actively Recruiting

14

IUCT Oncopole

Toulouse, France

Not Yet Recruiting

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Research Team

L

Lise Laclautre

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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