Actively Recruiting
BE WELL With Migraine: Brain Education and WELLness With Migraine
Led by Wake Forest University Health Sciences · Updated on 2026-04-29
286
Participants Needed
3
Research Sites
178 weeks
Total Duration
On this page
Sponsors
W
Wake Forest University Health Sciences
Lead Sponsor
N
National Center for Complementary and Integrative Health (NCCIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this randomized clinical trial is to evaluate two different non-drug, virtual treatment options designed to improve the lives of patients with migraine. Both interventions involve 8 weekly sessions and an online platform with additional content and learning. Participants can stay on all their medications during this study. Information from this study may help determine how to better treat migraine.
CONDITIONS
Official Title
BE WELL With Migraine: Brain Education and WELLness With Migraine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of migraine with or without aura with headache frequency of 4-20 days per month
- Migraine history of at least 1 year
- At least 18 years old
- Able to participate in 8 weekly online classes
- Willingness to complete baseline headache logs
- Headache Impact Test (HIT)-6 score greater than 50
- Fluent in English
- Completion of technology onboarding with the online platform
- Pregnant women less than or equal to 16 weeks gestation at enrollment
You will not qualify if you...
- Major unstable medical or psychiatric condition unsafe for participants or group environment
- Medication overuse headache with migraine treatment
- Pregnant women more than 16 weeks gestation at enrollment
- Unstable migraine treatment at enrollment: preventive treatment started within 12 weeks or acute treatment within 4 weeks
- Unwillingness to maintain stable medication dosages during study
- Failure to complete baseline headache logs
- Heavy alcohol and illicit drug use
- Participation in another intervention clinical trial that interferes with this study
- Experience with stress reduction training like daily meditation or mindfulness apps or prior MBSR experience
- Any other diagnoses or conditions that may prevent suitability or interfere with medical care, including COVID-positive test within 30 days of enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Cambridge Health Alliance - Center for Mindfulness and Compassion
Cambridge, Massachusetts, United States, 02141
Not Yet Recruiting
2
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States, 27157
Actively Recruiting
3
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, United States, 45229-3039
Not Yet Recruiting
Research Team
H
Hannah O'Brien
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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