The association between vitamin D receptor gene polymorphisms and bone mineral density at the spine, hip and whole-body in premenopausal women.
L M Salamone, R Ferrell, D M Black...
https://pubmed.ncbi.nlm.nih.gov/8845602Completed
Phase 3
Age: 45Years - 50Years
FEMALE
ID00000532
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2016-05-13
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
To determine if the increase in low density lipoprotein (LDL) cholesterol at the time of menopause could be ameliorated or prevented by an intensive dietary intervention. Also, to prevent the increase in body weight and associated changes in insulin, glucose, blood pressure, triglycerides, and high density lipoprotein cholesterol during the peri- to postmenopausal period.
CONDITIONS
Official Title
Women's Healthy Lifestyle Project: Cardiovascular Risk Factors and Menopause
Who Can Participate
Age: 45Years - 50Years
FEMALE
Eligibility Criteria
You may qualify if you...
Premenopausal women, ages 45-50 at entry.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
PREVENTION
Number of Arms
0
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Published Research Related To This Trial
Prevention of cardiovascular risk factor elevations in healthy premenopausal women.
L Simkin-Silverman, R R Wing, D H Hansen...
https://pubmed.ncbi.nlm.nih.gov/8524727Are menopausal symptoms associated with bone mineral density and changes in bone mineral density in premenopausal women?
L M Salamone, E Gregg, R L Wolf...
https://pubmed.ncbi.nlm.nih.gov/9651908Carotid atherosclerosis in premenopausal and postmenopausal women and its association with risk factors measured after menopause.
K Sutton-Tyrrell, H C Lassila, E Meilahn...
https://pubmed.ncbi.nlm.nih.gov/9626281Trp64Arg substitution in the beta 3-adrenergic receptor does not relate to body weight in healthy, premenopausal women.
M Moriarty, R R Wing, L H Kuller...
https://pubmed.ncbi.nlm.nih.gov/9376898Determinants of premenopausal bone mineral density: the interplay of genetic and lifestyle factors.
L M Salamone, N W Glynn, D M Black...
https://pubmed.ncbi.nlm.nih.gov/8889857Changing diet and exercise behaviors in individuals at risk for weight gain.
R R Wing
https://pubmed.ncbi.nlm.nih.gov/8581787Maintenance of cardiovascular risk factor changes among middle-aged women in a lifestyle intervention trial.
L R Simkin-Silverman, R R Wing, M A Boraz...
https://pubmed.ncbi.nlm.nih.gov/9787651Apolipoprotein E gene polymorphism and bone loss: estrogen status modifies the influence of apolipoprotein E on bone loss.
L M Salamone, J A Cauley, J Zmuda...
https://pubmed.ncbi.nlm.nih.gov/10703933Cytokine production and bone mineral density at the lumbar spine and femoral neck in premenopausal women.
L M Salamone, T Whiteside, D Friberg...
https://pubmed.ncbi.nlm.nih.gov/9817939