Actively Recruiting
Primary Versus Secondary Internal Limiting Membrane Peeling in Uncomplicated Retinal Detachment
Led by Sohag University · Updated on 2026-01-16
100
Participants Needed
1
Research Sites
12 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This trial studies patients with uncomplicated rhegmatogenous retinal detachment to compare two different timings of internal limiting membrane (ILM) peeling during eye surgery. The research aims to understand whether peeling the ILM during the first surgery or delaying it until the time of silicon oil removal affects outcomes. The study is randomized and triple-masked, led by Sohag University. Participants will receive 23-gauge pars plana vitrectomy (PPV) with silicon oil tamponade. They will be randomly assigned to one of two groups: Group A will have ILM peeling performed during the initial surgery, while Group B will have ILM peeling delayed until the silicon oil is removed. Both groups receive the same PPV and silicon oil treatment. During the study, patients will be followed from enrollment until three months after surgery to monitor for complications. The main outcome measured is the incidence of complications within this period. Participants will undergo regular postoperative evaluations to assess safety and treatment effects throughout the follow-up time. Total participation duration covers from surgery through three months post-operation.
CONDITIONS
Brief Title
1ry Versus 2ry ILM Peeling in RD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with uncomplicated rhegmatogenous retinal detcahment
- Age 18 years or older
You will not qualify if you...
- Proliferative vitreoretinopathy (PVR)
- Recurrent retinal detachment
- Tractional retinal detachment
- Macular hole retinal detachment
- Scleral buckling is indicated
- Macular scarring
- Previous pars plana vitrectomy (PPV)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 3 months post-surgery
Participants undergo pars plana vitrectomy (PPV) with either primary internal limiting membrane (ILM) peeling or delayed ILM peeling at the time of silicon oil extraction.
Approximately 3 postoperative visits
Trial Site Locations
Total: 1 location
1
Sohag Faculty of Medicine
Sohag, Sohag Governorate, Egypt, 82511
Actively Recruiting
Research Team
A
Alaa Sinjab, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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