Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07144748

68Ga-NYM096 PET/CT: Tracer Uptake in Various Kinds of Cancer

Led by Peking Union Medical College Hospital · Updated on 2025-09-05

120

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the uptake characteristics of 68Ga-NYM096 PET/CT imaging in various types of tumors, including both primary and metastatic cancer lesions. This prospective, single-center study aims to provide important insights into how different tumors take up this imaging tracer, helping to identify the most promising uses of 68Ga-NYM096 PET/CT for future cancer diagnosis and treatment assessment. Participants will receive a single intravenous dose of 68Ga-NYM096, with the amount adjusted based on body weight. After injection, a whole-body PET/CT scan will be performed approximately 45 to 75 minutes later to capture detailed images of tumor uptake. The study focuses on quantitative analysis of tracer uptake in cancer lesions, measuring factors such as lesion number, maximum standardized uptake value (SUVmax), and tumor-to-background ratio. During the study, participants will undergo the PET/CT imaging procedure and provide informed consent. Researchers will analyze the images to assess tracer uptake characteristics in confirmed tumors. Safety and compliance with study procedures will be monitored. The main outcome is the quantitative assessment of tumor lesions on the 68Ga-NYM096 PET/CT scan, evaluated from study completion to one month after. The study plans to enroll 120 patients with confirmed cancer diagnoses and will follow ethical guidelines throughout the research.

CONDITIONS

Brief Title

68Ga-NYM096 PET/CT in Various Kinds of Cancer

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Histopathologically confirmed primary or metastatic cancer
  • Expected survival of at least 3 months
  • Eastern Cooperative Oncology Group (ECOG) performance status of 2 or less
  • Provided written informed consent to participate
  • Willing and able to follow study procedures as judged by the investigator
Not Eligible

You will not qualify if you...

  • Received VEGF tyrosine kinase inhibitor treatment within 1 week before 68Ga-NYM096 PET/CT
  • Medical conditions that make study procedures unsafe or unsuitable
  • Pregnancy or breastfeeding
  • Severe claustrophobia preventing PET/CT imaging

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Imaging

Duration - 1 day

Participants receive a single intravenous dose of 68Ga-NYM096 followed by a dedicated whole-body PET/CT scan to evaluate tracer uptake in tumors.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Peking Union Medical College Hospital, Beijing, Beijing 100730

Beijing, China, 100730

Actively Recruiting

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Research Team

L

Li Huo, MD

W

Wenjia Zhu, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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