Actively Recruiting

All Genders
NCT05228106

68Ga-PSMA-617 PET/CT for PSMA-expressing Tumor: a Pragmatic Study

Led by Centre de recherche du Centre hospitalier universitaire de Sherbrooke · Updated on 2024-02-07

1000

Participants Needed

1

Research Sites

262 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project aims to monitor the innocuity/safety profile of cyclotron-produced \[68Ga\]-PSMA-617 PET imaging in PSMA-expressing cancers. It is a single-site, pragmatic, non-randomized and open-label study, with no control group. Although prostate cancers constitute the usual recommended population for this PET modality, recent evidences suggest that most solid tumors express substantial amount of PSMA in their neovasculature. As such, all cancers (excluding non-solid cancers) will be eligible for \[68Ga\]-PSMA-617 PET imaging in this trial, for as long as their tumors express PSMA. This study also aims to instigate the use of \[68Ga\]-PSMA-617 in the routine standard-of-care for detection and follow-up of eligible cancers. FInally, this project seeks to gather information about the impact on patient management this novel PET modality will have over the current standard-of-care.

CONDITIONS

Official Title

68Ga-PSMA-617 PET/CT for PSMA-expressing Tumor: a Pragmatic Study

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinical requisition for a 68Ga-PSMA-617 PET/CT signed by a referring doctor
  • Patients with suspected, proven or prior tumor expressing PSMA
  • Patient provides informed consent
Not Eligible

You will not qualify if you...

  • Patient refuses to participate
  • Prior severe anaphylactic reaction to 68Ga-PSMA-617

AI-Screening

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Trial Site Locations

Total: 1 location

1

CHUS

Sherbrooke, Quebec, Canada, J1H5N4

Actively Recruiting

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Research Team

S

Stéphanie Dubreuil

CONTACT

M

Michel Paquette, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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