Systolic Hypertension in the Elderly Program (SHEP): antihypertensive efficacy of chlorthalidone.
S B Hulley, C D Furberg, B Gurland...
https://pubmed.ncbi.nlm.nih.gov/4072925Completed
Phase 2
Age: 60Years +
All Genders
ID00000499
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2013-11-26
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
Sponsors
N
National Heart, Lung, and Blood Institute (NHLBI)
Lead Sponsor
N
National Institute on Aging (NIA)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The SHEP Pilot Study had six objectives, each designed to develop and test critical components of a full scale trial directed at the health consequences of treating isolated systolic hypertension (ISH) in the elderly. l. To estimate and compare the yield of participants for randomization into a clinical trial from various community groups using various recruitment techniques. 2\. To estimate compliance with the visit schedule and to the prescribed double-blind regimens. 3\. To estimate and compare the effectiveness of specified antihypertensive medications in reducing the blood pressure. 4\. To estimate and compare the unwanted effects of specified antihypertensive medication in an elderly population. 5\. To evaluate the feasibility and effectiveness of periodic behavioral assessment in this population. 6\. To develop and test methods of ascertaining stroke and other disease endpoints.
CONDITIONS
Official Title
Systolic Hypertension in the Elderly Program (SHEP) (Pilot Study)
Who Can Participate
Age: 60Years +
All Genders
Eligibility Criteria
You may qualify if you...
Men and women, aged 60 or over. Isolated systolic hypertension. Normal diastolic pressure of less than 90 mm Hg.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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Published Research Related To This Trial
Data quality in a distributed data processing system: the SHEP Pilot Study.
A Bagniewska, D Black, K Molvig...
https://pubmed.ncbi.nlm.nih.gov/3956210Systolic hypertension in the elderly program (SHEP). The first three months.
S B Hulley, D Feigal, C Ireland...
https://pubmed.ncbi.nlm.nih.gov/3511131Systolic Hypertension in the Elderly Program, Pilot Study (SHEP-PS): morbidity and mortality experience.
H M Perry, R H McDonald, S B Hulley...
https://pubmed.ncbi.nlm.nih.gov/3302150Predictors of cardiovascular events and mortality in the Systolic Hypertension in the Elderly Program pilot project.
D Siegel, L Kuller, N B Lazarus...
https://pubmed.ncbi.nlm.nih.gov/3303916Relation of life events to blood pressure control in the SHEP pilot trial.
T M Vogt, C C Ireland, M R Greenlick...
https://pubmed.ncbi.nlm.nih.gov/3293631Morbidity and mortality in the Systolic Hypertension in the Elderly Program (SHEP) pilot study.
H M Perry, W M Smith, R H McDonald...
https://pubmed.ncbi.nlm.nih.gov/2911834