Status:
TERMINATED
Brain Tissue Collection for Neuropathological Studies
Lead Sponsor:
National Institute of Mental Health (NIMH)
Conditions:
Bipolar Disorder
Depression
Eligibility:
All Genders
Brief Summary
The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders. Information gained from donated tissue may lead ...
Detailed Description
The knowledge of how affected tissue deviates from normal control tissue is an integral part of fully understanding a neurological or psychiatric disorder. The purpose of this protocol is to establish...
Eligibility Criteria
- INCLUSION CRITERIA:
Brain tissue is needed from individuals suffering from a variety of neuropsychiatric disorders, especially schizophrenia, but also anxiety disorders, suicide, bipolar disorder, depression, Tourette's Syndrome, drug addictions (PCP, cocaine, alcohol, heroin or the like) and any form of dementia. In addition, brains from normal individuals without a history of neuropsychiatric disease will be needed for controls.
EXCLUSION CRITERIA:
No living subjects are enrolled in this protocol. Tissue is obtained after death, with the permission of next of kin, or from existing institutions with appropriate samples via an MTA or other applicable agreement.
Brain tissue is excluded from collection if there is a previously known history of strokes, lesions, or other major neuropathological abnormalities prior to the consenting process.
Key Trial Info
Start Date :
May 29 1990
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 16 2017
Estimated Enrollment :
2161 Patients enrolled
Trial Details
Trial ID
NCT00001260
Start Date
May 29 1990
End Date
June 16 2017
Last Update
December 9 2019
Active Locations (3)
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1
Office of the Chief Medical Examiner
Washington D.C., District of Columbia, United States, 20003
2
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
3
Office of the Chief Medical Examiner
Fairfax, Virginia, United States, 22032