Status:
COMPLETED
Structure and Functional Status of Parotid Glands Exposed to Therapeutic Irradiation
Lead Sponsor:
National Institute of Dental and Craniofacial Research (NIDCR)
Conditions:
Radiation Injuries
Xerostomia
Eligibility:
All Genders
Brief Summary
Therapeutic irradiation to the head and neck for cancer damages salivary glands present in the radiation field. Despite long recognition of radiation-induced salivary hypofunction, and the associated ...
Detailed Description
Therapeutic irradiation to the head and neck for cancer damages salivary glands present in the radiation field. Despite long recognition of radiation-induced salivary hypofunction, and the associated ...
Eligibility Criteria
Age 21-80.
Diagnosis of head and neck cancer.
No surgery OR surgery with parotid glands intact.
Therapeutic radiation greater than or equal to 52 Gy.
Ambulatory.
No OR limited chemotherapy.
No Metastasis.
No allergy to Iodine.
No allergy to shellfish.
No metallic implants in head or neck.
No history of bleeding disorder.
No previous history of dry mouth (xerostomia).
No history of Sjogren's syndrome.
Negative HIV.
Key Trial Info
Start Date :
May 1 1996
Trial Type :
OBSERVATIONAL
End Date :
March 1 2000
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00001523
Start Date
May 1 1996
End Date
March 1 2000
Last Update
March 4 2008
Active Locations (1)
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1
National Institute of Dental And Craniofacial Research (NIDCR)
Bethesda, Maryland, United States, 20892