A two process model of sleep regulation.
A A Borbély
https://pubmed.ncbi.nlm.nih.gov/7185792Completed
All Genders
Healthy Volunteers
ID00001546
Circadian Regulation of Sleep in Habitual Short Sleepers and Long Sleepers
Led by National Institute of Mental Health (NIMH) · Updated on 2008-03-04
38
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Routine sleep duration varies greatly among individuals. The biological meaning of this variation is unknown. The term circadian rhythm refers to the biological clock that regulates the timing of falling asleep, waking up, and secretion of hormones, like melatonin. Melatonin is secreted at night. Previous studies have shown that melatonin may play a role in the regulation of sleep. The purpose of this study is to learn whether the duration of nighttime (nocturnal) melatonin secretion is longer in people with long regular sleep duration than people with short sleep duration. Researchers will compare levels of melatonin and cortisol, body temperature, sleepiness, and sleep in two extreme groups. Group one will be made up of people with short sleep duration lasting less than 6 hours. Group two will be made up of people with long sleep duration lasting more than 9 hours.
CONDITIONS
Official Title
Circadian Regulation of Sleep in Habitual Short Sleepers and Long Sleepers
Who Can Participate
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
Sleep greater than or equal to 9 hours almost every night.
Sleep less than or equal to 6 hours almost every night.
Between ages 20-30.
No medications, history of psychiatric illness, history of head injury.
No sleep disturbances.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
National Institute of Mental Health (NIMH)
Bethesda, Maryland, United States, 20892
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
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https://pubmed.ncbi.nlm.nih.gov/6165548