Actively Recruiting
Absorbable Versus Non-absorbable Sutures for Wound Closure in Carpal Tunnel Release A Randomized Controlled Trial
Led by Gelre Hospitals · Updated on 2025-08-26
2604
Participants Needed
2
Research Sites
308 weeks
Total Duration
On this page
Sponsors
G
Gelre Hospitals
Lead Sponsor
D
Deventer Ziekenhuis
Collaborating Sponsor
AI-Summary
What this Trial Is About
Carpal Tunnel Syndrome is a common condition causing numbness, pain, and weakness in the hand. Surgical decompression is the most effective treatment for this condition. After surgery, about 1.8% of patients develop wound infections, and this study evaluates whether the type of sutures used—absorbable versus non-absorbable—affects the risk of infection. This is a randomized controlled trial investigating infection rates related to suture type in carpal tunnel release surgery. Participants will undergo carpal tunnel release surgery, which involves cutting the flexor retinaculum to relieve pressure on the median nerve. The study compares the use of absorbable sutures, which dissolve over time, with non-absorbable sutures, which are later removed. Both suture types are commonly used in current clinical practice, but the study aims to determine if one leads to fewer wound infections. The primary outcome measured is the ASEPSIS wound score assessed 10 to 14 days after surgery. During the study, independent investigators will evaluate wound healing and infection signs using the ASEPSIS score. Researchers will also track antibiotic use, hand therapy, and extra outpatient visits. Patients are asked to record their pain scores for the first three weeks after surgery to monitor recovery. This study helps understand the impact of suture choice on wound healing and infection after carpal tunnel release surgery.
CONDITIONS
Official Title
abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Indication for carpal tunnel release
You will not qualify if you...
- Previous surgery for carpal tunnel syndrome
- Previous injection with corticosteroids
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Gelre Ziekenhuizen
Apeldoorn, Netherlands, 7334DZ
Actively Recruiting
2
Deventer Ziekenhuis
Deventer, Netherlands, 7416SE
Actively Recruiting
Research Team
P
Pauline Verhaegen, MD PHD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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