Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID05431101

Absorbable Versus Non-absorbable Sutures for Wound Closure in Carpal Tunnel Release A Randomized Controlled Trial

Led by Gelre Hospitals · Updated on 2025-08-26

2604

Participants Needed

2

Research Sites

308 weeks

Total Duration

On this page

Sponsors

G

Gelre Hospitals

Lead Sponsor

D

Deventer Ziekenhuis

Collaborating Sponsor

AI-Summary

What this Trial Is About

Carpal Tunnel Syndrome is a common condition causing numbness, pain, and weakness in the hand. Surgical decompression is the most effective treatment for this condition. After surgery, about 1.8% of patients develop wound infections, and this study evaluates whether the type of sutures used—absorbable versus non-absorbable—affects the risk of infection. This is a randomized controlled trial investigating infection rates related to suture type in carpal tunnel release surgery. Participants will undergo carpal tunnel release surgery, which involves cutting the flexor retinaculum to relieve pressure on the median nerve. The study compares the use of absorbable sutures, which dissolve over time, with non-absorbable sutures, which are later removed. Both suture types are commonly used in current clinical practice, but the study aims to determine if one leads to fewer wound infections. The primary outcome measured is the ASEPSIS wound score assessed 10 to 14 days after surgery. During the study, independent investigators will evaluate wound healing and infection signs using the ASEPSIS score. Researchers will also track antibiotic use, hand therapy, and extra outpatient visits. Patients are asked to record their pain scores for the first three weeks after surgery to monitor recovery. This study helps understand the impact of suture choice on wound healing and infection after carpal tunnel release surgery.

CONDITIONS

Official Title

abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Indication for carpal tunnel release
Not Eligible

You will not qualify if you...

  • Previous surgery for carpal tunnel syndrome
  • Previous injection with corticosteroids

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Gelre Ziekenhuizen

Apeldoorn, Netherlands, 7334DZ

Actively Recruiting

2

Deventer Ziekenhuis

Deventer, Netherlands, 7416SE

Actively Recruiting

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Research Team

P

Pauline Verhaegen, MD PHD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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