Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07312123

A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome

Led by Hospital Universiti Sains Malaysia · Updated on 2026-04-23

84

Participants Needed

1

Research Sites

59 weeks

Total Duration

On this page

Sponsors

H

Hospital Universiti Sains Malaysia

Lead Sponsor

B

BREGO Life Sciences Sdn Bhd

Collaborating Sponsor

AI-Summary

What this Trial Is About

Carpal Tunnel Syndrome (CTS) is a common condition that causes numbness, tingling, pain, and weakness in the hand due to compression of the median nerve at the wrist. It can affect daily activities, work performance, and quality of life. While surgery is effective in severe cases, many patients with mild to moderate CTS are initially treated with non-surgical options such as splinting and medications. However, the effectiveness of oral supplements for CTS remains uncertain. This clinical study aims to evaluate whether an oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B complex can safely reduce symptoms and improve hand function in patients with Carpal Tunnel Syndrome. These supplements are believed to have antioxidant, anti-inflammatory, and nerve-protective properties, which may help reduce nerve irritation and improve nerve recovery. Participants in this study will be randomly assigned to receive either the oral supplement combination or a comparator treatment. The study is single-blinded, meaning participants will not know which treatment they are receiving. Symptoms such as pain, numbness, and hand function will be assessed over a defined follow-up period using clinical evaluation and standardized questionnaires. The main hypothesis of this study is that patients receiving the oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B will experience greater improvement in symptoms and functional outcomes compared to those who do not receive the combination, without significant side effects. The results of this study may help determine whether this oral supplement combination can be used as an effective and safe conservative treatment option for patients with Carpal Tunnel Syndrome, potentially reducing the need for invasive procedures.

CONDITIONS

Official Title

A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age more than 18 years old
  • Symptoms and physical examination consistent with Carpal Tunnel Syndrome
  • Patients scheduled for Carpal Tunnel release surgery
Not Eligible

You will not qualify if you...

  • Pregnant or breast-feeding women
  • Patients with history of trauma in the dominant hand

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Pakar Universiti Sains Malaysia

Kubang Kerian, Kelantan, Malaysia, 16150

Actively Recruiting

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Research Team

N

Nurhakim Bin Ibrahim, MBBCH

CONTACT

A

ASSOCIATE PROFESSOR ABDUL NAWFAR BIN SADAGATULLAH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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