Actively Recruiting
A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome
Led by Hospital Universiti Sains Malaysia · Updated on 2026-04-23
84
Participants Needed
1
Research Sites
59 weeks
Total Duration
On this page
Sponsors
H
Hospital Universiti Sains Malaysia
Lead Sponsor
B
BREGO Life Sciences Sdn Bhd
Collaborating Sponsor
AI-Summary
What this Trial Is About
Carpal Tunnel Syndrome (CTS) is a common condition that causes numbness, tingling, pain, and weakness in the hand due to compression of the median nerve at the wrist. It can affect daily activities, work performance, and quality of life. While surgery is effective in severe cases, many patients with mild to moderate CTS are initially treated with non-surgical options such as splinting and medications. However, the effectiveness of oral supplements for CTS remains uncertain. This clinical study aims to evaluate whether an oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B complex can safely reduce symptoms and improve hand function in patients with Carpal Tunnel Syndrome. These supplements are believed to have antioxidant, anti-inflammatory, and nerve-protective properties, which may help reduce nerve irritation and improve nerve recovery. Participants in this study will be randomly assigned to receive either the oral supplement combination or a comparator treatment. The study is single-blinded, meaning participants will not know which treatment they are receiving. Symptoms such as pain, numbness, and hand function will be assessed over a defined follow-up period using clinical evaluation and standardized questionnaires. The main hypothesis of this study is that patients receiving the oral combination of alpha-lipoic acid, Vitamin E, and Vitamin B will experience greater improvement in symptoms and functional outcomes compared to those who do not receive the combination, without significant side effects. The results of this study may help determine whether this oral supplement combination can be used as an effective and safe conservative treatment option for patients with Carpal Tunnel Syndrome, potentially reducing the need for invasive procedures.
CONDITIONS
Official Title
A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age more than 18 years old
- Symptoms and physical examination consistent with Carpal Tunnel Syndrome
- Patients scheduled for Carpal Tunnel release surgery
You will not qualify if you...
- Pregnant or breast-feeding women
- Patients with history of trauma in the dominant hand
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hospital Pakar Universiti Sains Malaysia
Kubang Kerian, Kelantan, Malaysia, 16150
Actively Recruiting
Research Team
N
Nurhakim Bin Ibrahim, MBBCH
CONTACT
A
ASSOCIATE PROFESSOR ABDUL NAWFAR BIN SADAGATULLAH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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