Study of Oral Alpha-Lipoic Acid, Vitamin E, and Vitamin B Supplements to Improve Symptoms and Hand Function After Carpal Tunnel Surgery in Adults

What this Trial Is About

Carpal Tunnel Syndrome CTS causes numbness, tingling, pain, and weakness in the hand due to pressure on the median nerve at the wrist. This condition can affect daily activities, work, and quality of life. Researchers are studying whether taking an oral combination of alpha-lipoic acid, Vitamin E, and a Vitamin B complex can safely reduce CTS symptoms and improve hand function after surgery. This study is sponsored by Hospital Universiti Sains Malaysia and involves a single-blinded design where participants do not know which treatment they receive. Participants will be randomly assigned to one of two groups one receiving the oral supplement combination of alpha-lipoic acid, Vitamin E, and Vitamin B complex daily in capsule form, and the other receiving an oral Vitamin B complex as an active comparator. Both treatments are given once daily throughout the study. This approach aims to assess whether the supplement combination offers greater symptom relief and functional improvement compared to the comparator. During the study, symptoms such as pain and numbness will be measured using the Boston Carpal Tunnel Syndrome Questionnaire and a visual analog scale at the start, 12 weeks, and 24 weeks. Researchers will track changes in these scores to evaluate the treatments. Participant safety and side effects will be monitored, and the total study duration includes follow-up assessments to observe improvements and functional outcomes.

A Study to See Whether Taking a Mix of Vitamins Can Help Adults Recover Better After Surgery for Carpal Tunnel Syndrome