Positive effects of Red Bull® Energy Drink on driving performance during prolonged driving.
Monique A J Mets, Sander Ketzer, Camilla Blom...
https://pubmed.ncbi.nlm.nih.gov/21063868Actively Recruiting
Phase Not Applicable
Age: 18Years - 45Years
All Genders
Healthy Volunteers
ID07588022
Acute Effects of an Explosive Cocktail With Energy Drinks That is Trendy Among Young People, the J e4gerbomb
Led by Fundació Institut Germans Trias i Pujol · Updated on 2026-05-14
24
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
Sponsors
F
Fundació Institut Germans Trias i Pujol
Lead Sponsor
P
Plan Nacional sobre Drogas
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying the effects of J e4gerbombs, a popular mix of J e4germeister liquor and energy drinks, compared to drinking alcohol alone during binge-drinking episodes. Binge drinking involves consuming a large amount of alcohol quickly to become intoxicated, which is a serious health concern among young people in Spain. This trial aims to assess how J e4gerbombs influence alcohol effects, stimulation, coordination, reaction time, vision, stress hormone responses, and hangover symptoms. Participants receive drinks in a randomized, double-blind, placebo-controlled setup with three groups: J e4germeister plus energy drink, J e4germeister plus a placebo energy drink, and placebo alcohol plus placebo energy drink. The total drink volume is split into five doses given every 10 minutes over 45 minutes to simulate binge drinking. Dosages differ for men and women based on body weight and alcohol content. During the study, participants undergo various tests and assessments including reaction time, breath alcohol and saliva caffeine levels, visual acuity, coordination tasks, feelings of drunkenness and drowsiness, heart rate, blood pressure, hormone levels, and hangover symptoms over several hours after drinking. Safety is monitored through physical exams, ECG, and blood and urine tests. The study lasts several hours for each participant, measuring both immediate and lasting effects of the drinks.
CONDITIONS
Brief Title
Acute Effects of Jägermeister With Energy Drinks (Jägermbomb)
Who Can Participate
Age: 18Years - 45Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Men and women aged 18 to 45 years
- Weight between 50-90 kg for men and 55-80 kg for women, with BMI between 19-28 kg/m2 (exceptions allowed by the investigator)
- Occasional binge drinking at least once per month and social alcohol consumption
- Consume at least 7 drinks with methylxanthines weekly and have consumed energy drinks at least once
- Able to understand and agree to study procedures and sign informed consent
- No organic or psychiatric disorders based on history and physical exam
- Normal or near-normal ECG, blood, and urine tests as judged by the investigator
You will not qualify if you...
- Not meeting inclusion criteria
- History or current gastrointestinal, liver, or kidney disorders affecting drug absorption or metabolism
- Current substance use disorder (except nicotine); mild past disorder allowed
- History or presence of psychiatric disorders, alcoholism, drug abuse, or regular use of psychoactive drugs
- Participation in drug or nutraceutical trials in past 12 weeks
- Major illness or surgery in past 3 months
- Intolerance or serious adverse reactions to alcohol
- Regular medication use in past month (except certain supplements or vitamins)
- Smoking more than 5 cigarettes per day
- Daily alcohol consumption over 20 g for women or 40 g for men
- High daily intake of stimulant drinks over past 3 months
- Inability to understand study nature and procedures
- Positive tests for hepatitis B, C, or HIV
- Pregnant or breastfeeding women or those not using reliable contraception
- Severe amenorrhea or premenstrual syndrome in women
AI-Screening
AI-Powered Screening
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1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - Approximately 45 minutes per treatment session
Participants receive multiple oral doses of Jägermeister mixed with energy drink, a placebo energy drink, or placebo drinks in a randomized crossover design to study acute effects.
Multiple treatment visits scheduled for crossover sessions
Monitoring
Duration - Up to 8 hours after each treatment session
Participants are monitored for up to 8 hours after each treatment session to assess reaction time, concentration of ethanol and caffeine, physiological and subjective effects.
Assessments conducted during each treatment visit
Trial Site Locations
Total: 1 location
1
Hospital Universitari Germans Trias i Pujol-IGTP
Barcelona, Spain
Actively Recruiting
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Research Team
C
Clara Pérez-Mañá, MD, PhD
S
Soraya Martín
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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