What is this study about the effects of Je4gerbombs on alcohol drinking?

This study is evaluating how Je4gerbombs, a mix of Je4germeister and energy drinks, affect alcohol intoxication compared to alcohol alone during binge drinking. Researchers want to understand if this popular drink changes stimulation, coordination, reaction time, hormone responses, and hangover symptoms. The study is sponsored by Fundacif3 Institut Germans Trias i Pujol.

Who may be eligible for this alcohol drinking clinical trial?

Adults aged 18 to 45 who have experience with binge drinking and energy drinks may be eligible. Both men and women who meet weight and health criteria can participate. People with certain medical or psychiatric conditions or who drink or smoke heavily may not qualify. Please review eligibility criteria for more details.

Is there any cost to participate in this alcohol drinking clinical trial?

Study-related care, including the study drinks and all trial visits, is provided at no cost. However, any personal travel or other expenses related to participating are not guaranteed to be covered. Participants should plan accordingly.

Actively Recruiting

Phase Not Applicable

Age: 18Years - 45Years

All Genders

Healthy Volunteers

ID07588022

Study of the Immediate Effects of Jgermeister Mixed With Energy Drinks Jgerbomb Compared to Alcohol Alone in Adults Aged 18 to 45

Led by Fundació Institut Germans Trias i Pujol · Updated on 2026-05-14

Participants Needed

Research Sites

13 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are studying the effects of Je4gerbombs, a popular mix of Je4germeister liquor and energy drinks, compared to drinking alcohol alone during binge-drinking episodes. Binge drinking involves consuming a large amount of alcohol quickly to become intoxicated, which is a serious health concern among young people in Spain. This trial aims to assess how Je4gerbombs influence alcohol effects, stimulation, coordination, reaction time, vision, stress hormone responses, and hangover symptoms. Participants receive drinks in a randomized, double-blind, placebo-controlled setup with three groups Je4germeister plus energy drink, Je4germeister plus a placebo energy drink, and placebo alcohol plus placebo energy drink. The total drink volume is split into five doses given every 10 minutes over 45 minutes to simulate binge drinking. Dosages differ for men and women based on body weight and alcohol content. During the study, participants undergo various tests and assessments including reaction time, breath alcohol and saliva caffeine levels, visual acuity, coordination tasks, feelings of drunkenness and drowsiness, heart rate, blood pressure, hormone levels, and hangover symptoms over several hours after drinking. Safety is monitored through physical exams, ECG, and blood and urine tests. The study lasts several hours for each participant, measuring both immediate and lasting effects of the drinks.

CONDITIONS

Brief Title

Acute Effects of Jägermeister With Energy Drinks (Jägermbomb)

Who Can Participate

Age: 18Years - 45Years

All Genders

Healthy Volunteers

Eligibility Criteria

You may qualify if you...

Men and women aged 18 to 45 years
Weight between 50-90 kg for men and 55-80 kg for women, with BMI between 19-28 kg/m2 (exceptions allowed by the investigator)
Occasional binge drinking at least once per month and social alcohol consumption
Consume at least 7 drinks with methylxanthines weekly and have consumed energy drinks at least once
Able to understand and agree to study procedures and sign informed consent
No organic or psychiatric disorders based on history and physical exam
Normal or near-normal ECG, blood, and urine tests as judged by the investigator

You will not qualify if you...

Not meeting inclusion criteria
History or current gastrointestinal, liver, or kidney disorders affecting drug absorption or metabolism
Current substance use disorder (except nicotine); mild past disorder allowed
History or presence of psychiatric disorders, alcoholism, drug abuse, or regular use of psychoactive drugs
Participation in drug or nutraceutical trials in past 12 weeks
Major illness or surgery in past 3 months
Intolerance or serious adverse reactions to alcohol
Regular medication use in past month (except certain supplements or vitamins)
Smoking more than 5 cigarettes per day
Daily alcohol consumption over 20 g for women or 40 g for men
High daily intake of stimulant drinks over past 3 months
Inability to understand study nature and procedures
Positive tests for hepatitis B, C, or HIV
Pregnant or breastfeeding women or those not using reliable contraception
Severe amenorrhea or premenstrual syndrome in women

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Approximately 45 minutes per treatment session

Participants receive multiple oral doses of Jägermeister mixed with energy drink, a placebo energy drink, or placebo drinks in a randomized crossover design to study acute effects.

Multiple treatment visits scheduled for crossover sessions

Monitoring

Duration - Up to 8 hours after each treatment session

Participants are monitored for up to 8 hours after each treatment session to assess reaction time, concentration of ethanol and caffeine, physiological and subjective effects.

Assessments conducted during each treatment visit