Actively Recruiting

Age: 18Years +
All Genders
ID03883711

Acute Myocardial Infarction From Clinical Presentation to Strategy Treatment

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2026-01-30

11000

Participants Needed

3

Research Sites

208 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are conducting an observational study called AMIPE to collect and analyze data on patients with acute coronary syndrome or myocardial injury. The study is both retrospective and prospective, enrolling patients admitted to participating hospitals from January 1, 2016, to December 31, 2023. The goal is to improve understanding and knowledge about these heart conditions by creating a detailed database of patient characteristics and outcomes. The study involves gathering information from patient medical records during hospitalization and requires written informed consent for prospective participants. No specific treatments are assigned as this is an observational study; all diagnostic and therapeutic interventions follow established guidelines and good clinical practice. Researchers will document patient characteristics, long-term outcomes, and treatment regimens. Participants will be monitored for major outcomes such as all-cause mortality and major adverse cardiac events over 1, 3, and 5 years. Additional data on cardiovascular risk factors, clinical presentations, and complications will also be collected. Statistical analyses including univariate and multivariate methods will be used to evaluate these outcomes. The study is led by IRCCS Azienda Ospedaliero-Universitaria di Bologna and aims to provide new scientific evidence about these heart conditions.

CONDITIONS

Brief Title

Acute Myocardial Infarction: Prognostic and Therapeutic Evaluation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient aged > 18 years old
  • Diagnosis of acute coronary syndrome or myocardial injury
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Under age 18
  • Unable to provide informed consent

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - At admission and during hospital stay

Participants undergo diagnostic assessments related to acute coronary syndrome or myocardial injury, with data collected from in-hospital medical records.

1 to several visits depending on hospital stay

Long-term Monitoring

Duration - Up to 5 years

Participants are followed over time to document long-term outcomes, cardiovascular risk factors, and clinical presentations up to 5 years after initial diagnosis.

Periodic follow-up visits over 5 years

Trial Site Locations

Total: 3 locations

1

Policlinico Sant'Orsola-Malpighi, Cardiology Department

Bologna, Bologna, Italy, 40138

Actively Recruiting

2

Ospedale Maggiore Carlo Alberto Pizzardi

Bologna, BO, Italy, 40133

Actively Recruiting

3

Ospedale Morgagni - Pierantoni

Forlì, FC, Italy, 47121

Actively Recruiting

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Research Team

C

Carmine Pizzi, Prof

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

American College of Cardiology/American Heart Association/European Society of Cardiology/World Heart Federation universal definition of myocardial infarction classification system and the risk of cardiovascular death: observations from the TRITON-TIMI 38 trial (Trial to Assess Improvement in Therapeutic Outcomes by Optimizing Platelet Inhibition With Prasugrel-Thrombolysis in Myocardial Infarction 38).

Marc P Bonaca, Stephen D Wiviott, Eugene Braunwald...

https://pubmed.ncbi.nlm.nih.gov/22199016

Type 1 and 2 Myocardial Infarction and Myocardial Injury: Clinical Transition to High-Sensitivity Cardiac Troponin I.

Yader Sandoval, Stephen W Smith, Anne Sexter...

https://pubmed.ncbi.nlm.nih.gov/28739197

Impact of admission hyperglycemia on short and long-term prognosis in acute myocardial infarction: MINOCA versus MIOCA.

Pasquale Paolisso, Alberto Foà, Luca Bergamaschi...

https://pubmed.ncbi.nlm.nih.gov/34560876