Physical Activity Program to Improve Walking and Quality of Life in Adults with Lower Limb Peripheral Arterial Disease

What this Trial Is About

Peripheral arterial disease affects about 12.2% of people in France and causes pain during walking due to narrowed arteries limiting blood flow to the muscles. This pain varies depending on where the blood flow is limited in the legs and has not been studied in detail regarding its effect on walking and muscle activity. These limitations significantly reduce quality of life and are linked to higher mortality, making improvement in physical function and symptom relief crucial for patients. The study compares two types of adapted physical activity programs for patients with lower limb peripheral arterial disease. One program targets muscle strengthening specifically in areas with reduced blood flow, while the other follows a standard muscle strengthening routine without this localization. Both programs aim to improve walking ability and overall physical capacity over a 12-week period. Participants will engage in either targeted or general adapted physical activity and be monitored for changes in walking distance, walking ability, balance, muscle strength, neuromuscular activity, and quality of life. Assessments will occur 12 weeks after starting the program to evaluate the effect of the treatments. The study is randomized and open-label, with no blinding, and participation lasts for about 12 weeks.

Adapted Physical Activity in Patients With Lower Limb Peripheral Arterial Disease